波强法测定脉搏波传导速度的临床应用价值  

A new measurement of pulse wave velocity by wave intensity analysis

作　　者：杨勇[1] 刘杰[1] 曹铁生[1] 段云友[1] 王臻[1] 杨一林[1] 许磊[1] 赵联璧[1] 

机构地区：[1]第四军医大学唐都医院超声科,西安710038

出　　处：《中华超声影像学杂志》2012年第6期474-477,共4页Chinese Journal of Ultrasonography

基　　金：国家自然科学基金（81171348）

摘　　要：目的探讨波强法（wI）所测脉搏波传导速度（PWV）的可重复性，并与传统平面压力波法进行比较，探讨其临床应用价值。方法应用多普勒超声仪的波强分析系统，测量110例门诊志愿者右侧肱动脉和胫后动脉Rw，时间，由此计算右侧臂踝脉搏波传导速度（baPwV），同时用压力波法（VP1000）测量该值；然后再随机选取其中30例受检者重复上述检查。采用配对t检验比较两种方法测值的差异，并分析其直线相关性；最后应用Bland Altman法分析这两种方法的一致性及各自观察者内部的可重复性。结果baPWV的均值分别为波强法中RW1段（13．03±1．93）m／s，压力波法（12．05±2．02）m／S，两种方法的测值差异有统计学意义（P〈0．001），两者差值平均为（o．98±1．1）m／s，其95％一致性界限为（-1．18m／s，3．14m／s）。波强法中R—W，段和压力波法具有较高的直线相关性（r=0．85，P〈0．001）；其各自观察者内部的重复测量变异率分别为8．2％和7．0％。结论瞬时波强法可为临床测量PwV提供一种简便无创的新方法，并与标准压力波法有很好的相关性和一致性。Objective To test the reproducibility of wave intensity （WI） analysis derived measurements of pulse wave velocity （PWV）, and to compare it with the traditional method-applanation tonometry. Methods One hundred and ten outpatient volunteers were enrolled in the study. The R-W1 of right brachial artery and right posterior tibial artery were measured through WI in diagnostic ultrasound equipment （Aloka α10） ,and were used to calculate the right brachial artery PWV which were also measured by tonometry （VP-1000） simutaneouslylthus 30 of these volunteers were randomly selected to repeat the above examinations in the same session. Differences between the two methods were investigated by means of a paired t-test,and their linear correlations were also analyzed. Bland Altman method was used to analyze the agreement between the two methods and their intraobserver intrasession variabilities. Results Mean baPWVs determined by WI and tonometry were （13.03 ± 1.93）m/s and （12.05 ± 2.02） m/s,respectively （P 〈0. 001 ）, and the mean of their difference was （0.98± 1.1 ）m/s giving 95% limits of agreement of （ - 1.18 m/s,3.14 m/s）. Values of PWV obtained by the two systems were highly correlated（ r = 0.85, P〈0.001 ）, with their intraobserver intrasession variabilities being 8.2% and 7.0%, respectively. Conclusions WI provides a new noninvasive and convenient method to measure PWV with good agreement and similar reproducibility to the standard tonometry system.

关 键 词：超声心动描记术 动脉僵硬度 动脉弹性 脉搏波传导速度 

分 类 号：R544.1[医药卫生—心血管疾病]