IgA肾病合并代谢综合征患者生活方式干预的临床研究  

Clnical study of lifestyle intervention in treatment of IgA nephropathy merged with metabolic syndrome

作　　者：刘翠珍[1] 陈梅[1] 

机构地区：[1]泰安市中心医院,山东271000

出　　处：《社区医学杂志》2012年第12期35-37,共3页Journal Of Community Medicine

摘　　要：目的观察IgA肾病合并代谢综合征(MS)患者生活方式干预的临床效果。方法选择我科2007-2011年确诊IgA肾病合并代谢综合征患者62例,随机分为2组,研究组为生活方式干预(运动锻炼、合理饮食、戒烟限酒)合并药物治疗组,对照组为单用药物治疗组6,个月后比较两组代谢综合征相关的参数及24小时尿蛋白定量、肾功能等。结果研究组生活方式干预6个月后,代谢综合征相关危险因素,如肥胖、高血压、高血糖、高甘油三酯、高尿酸均有明显改善(,P<0.01,或P<0.05)。研究组与对照组治疗后比较肾功能明显好转,24小时尿蛋白定量明显降低(P<0.05)。结论对IgA肾病合并代谢综合征患者应用活方式干预联合药物治疗,可有效控制病情的进展。Objective To observe the clinical efficacy of lifestyle intervention in treatment of IgA nephropathy merged with metabolic syndrome. Methods 62 patients were randomly divided into treatment group and control group, each group contained 31 cases. The treatment group was given Lifestyle intervention combined with drug treatment , and the control group with given drug treatment, and both group continued for therapeutical period of 6 months. Results Study group with lifestyle intervention after 6 months ,the risk factors associated with metabohc syndrome, such as obesity, hypertension, high blood suger,hiagh triglycerides, high uric acid were significantly improved（ P 〈 0. 01 or P 〈 0.05 ）. Compared with the control group,the renal function of study group was significantly improved and 24 - h urinary protein excertion decreased significantly （ P 〈 0.05）. Conclusion Lifestyle intervention combined with drug treatment could definitely correct metabolic factors ,reduce urine protein and improve renal function in treatment of IgA nephropathy merged with metabolic syndrome ,can effectively control the progress of the disease.

关 键 词：IGA肾病 代谢综合征 生活方式 干预治疗 

分 类 号：R692[医药卫生—泌尿科学]