妊娠期肝内胆汁淤积症146例围生结局分析  

PERINATAL OUTCOMES OF INTRAHEPATIC CHOLESTASIS OF PREGNANCY:ANALYSIS OF 146

作　　者：刘杨[1] 

机构地区：[1]兖矿集团总医院妇产科,山东省邹城市273500

出　　处：《中国煤炭工业医学杂志》2012年第6期808-809,共2页Chinese Journal of Coal Industry Medicine

摘　　要：目的探讨妊娠期肝内胆汁淤积症(ICP)的肝功能及总胆汁酸升高程度与围生儿预后的关系。方法回顾性分析在兖矿集团总医院的146例ICP妊娠孕妇的临床资料。根据肝功能及总胆汁酸指标高低分为轻-中度ICP组(A组)与重度ICP组(B组),并对二组ICP孕妇分娩结局进行综合分析。结果 B组孕妇早产发生率、胎儿宫内窘迫、新生儿窒息、围生儿病死率、剖宫产率等均明显高于A组(P<0.05)。结论重度ICP组产妇母胎结局不良,临床上加强母胎监护和生化指标的监测、早期干预,适时终止妊娠,可以改善母胎结局。Objective To explore the relationship between intrahepatic cholestasis of pregnancy （ICP） and the prognosis of neonates. Methods The clinical data of 146 cases of ICP in author＇s hospital were ret- rospectively analyzed. According to the level of liver function and serum cholicacid, the patients were divid- ed into low moderate ICP group（group A） and severe ICP group（group B）. The perinatal outcome of the two groups was analyzed. Results The occurrence of premature delivery,fetal distress,neonatal asphyxia, neonatal death rate and abdominal delivery were higher in the group A than those in the group B（P〈0. 05）. Conclusion There is bad outcome in severe ICP group. Enhancing hepatic function test,biochemistry indexes measurement and timely termination of pregnancy can improve the outcome of matal-fetal.

关 键 词：妊娠期 并发症 妊娠期胆汁淤积症 围生儿 预后 

分 类 号：R714.255[医药卫生—妇产科学]