2009—2010年苏州儿童医院呼吸道感染3529例鲍曼不动杆菌分布及耐药性分析  

Analysis of prevalence and antibiotic resistance of Acinetobacter baumannii in children with acute respiratory tract infection in Suzhou 2009-2010

作　　者：蔡利红[1] 季伟[1] 孙慧明[1] 李蓓荃[1] 严永东[1] 陶云珍[1] 丁云芳[1] 

机构地区：[1]苏州大学附属儿童医院呼吸科,江苏苏州215003

出　　处：《中国实用儿科杂志》2012年第6期440-442,共3页Chinese Journal of Practical Pediatrics

基　　金：苏州社会发展科技计划项目(No.SS0702)

摘　　要：目的分析呼吸道感染患儿鲍曼不动杆菌的感染情况及其耐药性。方法对2009年1月至2010年12月在苏州大学附属儿童医院呼吸科住院的3529例急性呼吸道感染患儿,采用无菌负压吸引法采集新鲜痰液,进行鲍曼不动杆菌培养、分离,并采用定量MIC法进行药敏试验,观察及分析呼吸道鲍曼不动杆菌感染情况及相关因素。结果 3529例急性呼吸道感染患儿分离到1523株致病菌,其中鲍曼不动杆菌44株,占2.89%;在不同的性别、年龄组感染率无差别;四季分布不同,以夏秋季节多见。鲍曼不动杆菌对氨苄西林、呋喃妥因、头孢唑林的耐药率为100%,对头孢他啶、头孢噻肟、头孢吡肟的耐药率上升,未发现对头孢哌酮舒巴坦、妥布霉素、左氧氟沙星、氨苄西林舒巴坦、阿米卡星、亚胺培南的耐药菌株。结论苏州儿童医院急性呼吸道感染患儿鲍曼不动杆菌的感染率与季节有关,无性别、年龄差异;对氨苄西林、呋喃妥因、头孢唑林耐药,对第三、四代头孢菌素的耐药率上升。Objective To analye the prevalence,clinical characteristics and antibiotic resistance of Acinetobacter baumannii （AB） in children with acute respiratory tract infection in Suzhou. Methods Data of sputum culture of 3529 hospitalized child patients with acute respiratory tract infection from January 2009 to December 2010 were collected.The incidence of positive AB and the rate of resistance to different antibiotics were calculated. Results Of the total 3529 cases,44 ABs were detected.The infection rate had no relation with sex or age but was related to season, which was more frequent in summer and autumn.The resistance to ampicillin, furantoin and cephazolin was completely with the adscendent resistance rates to ceftazidime, cefotaxime and cefpirome; isolates resistance to cefoperazone sodium, tobramycine, levofloxacin, ampicillin sulbactam, amikacin and imipenem was not found. Conclusion The infection of AB in children with acute respiratory tract infection is closely related to season, but has no relation with sex or age in Suzhou.It is completely resistant to ampicillin, furantoin and cephazolin; the resistance rates to the third and fourth generation of cephalosporin step up.

关 键 词：儿童 呼吸道感染 鲍曼不动杆菌 耐药性 

分 类 号：R72[医药卫生—儿科]