唐古特红景天提取工艺研究  

Study on the Optimized Extraction Technology of Rhodiola Algida

作　　者：贺美艳 张小龙[2] 

机构地区：[1]三金集团湖南三金制药有限责任公司,湖南常德415001 [2]中国科学院成都生物研究所,成都610041

出　　处：《中国现代应用药学》2012年第6期495-497,共3页Chinese Journal of Modern Applied Pharmacy

基　　金："十一五"国家科技重大专项(2009ZX09501-015)

摘　　要：目的确定唐古特红景天药材的最佳提取工艺。方法采用超声、回流、冷浸法,采用L9(34)正交试验法,考察提取温度、乙醇浓度、溶剂量、提取时间4因素对红景天苷、酪醇含量和提取率的影响。结果回流提取为最适提取方法,最佳提取工艺条件为:8倍量50%乙醇80℃提取2次,每次提取1.0 h。结论该研究结果为有效利用唐古特红景天资源及其工业生产提供了依据。OBJECTIVE To optimize the extraction technology of Rhodiola algida. METHODS Rhodiola algida was extracted by ultrasonic, refluxing and cold soaking extraction, respectively. The extraction rate, content of salidroside and p-tyrosol were chosen as the assessment index by using the orthogonal design. The effects of ethanol content, solvent volume, extracting time （hour） and extraction temperature were investigated. RESULTS The results indicated that the refluxing extraction was the best method. The optimized extraction process conditions were as follows： adding 8 fold of 50% ethanol, extracting for 1.0 h and 2 times at 80 ℃. CONCLUSION This study will provide a reference to the research of Rhodiola algida and industrial production.

关 键 词：唐古特红景天 红景天苷 酪醇 正交试验 

分 类 号：R284.2[医药卫生—中药学]