猪繁殖与呼吸综合征病毒变异株感染猪超微结构研究  

Ultrastructure Study of Swine Infected with Shanxi Variant Strain of Porcine Reproductive and Respiratory Syndrome Virus

作　　者：孟帆[1] 姚敬明[1] 吴忻[1] 韩一超[1] 樊振华[1] 范瑞文[2] 王娟萍[1] 候燕平[2] 刘文俊[1] 米瑞娟[1] 

机构地区：[1]山西省农业科学院畜牧兽医研究所,山西太原030032 [2]山西农业大学,山西太谷030801

出　　处：《中国畜牧兽医》2012年第6期196-199,共4页China Animal Husbandry & Veterinary Medicine

基　　金：山西省科技攻关项目(20080311036-1)

摘　　要：利用透射电镜对山西省PRRSV变异株感染猪的肺脏、脾脏、肝脏、肾脏、淋巴结等组织进行超微病理变化的观察。试验结果发现,肺脏、脾脏、肝脏、肾脏、淋巴结各组织细胞均被不同程度地感染,各种细胞器遭受普遍的膜结构损伤,而以线粒体和细胞核变化较为严重。本研究为阐明PRRSV变异株感染猪的致病机理提供了理论依据。The ultra microstructure of lung, spleen, liver,lymph node and other tissues from pigs infected with Shanxi va- riant strain of PRRSV were observed by transmission electron microscopy （TErn）. Results showed that the pulmonary macro- phages, the hepatoeytes and the lymphocytes in the lymph nodes and the spleen were infected to different degrees, where the membranous structures of organelles was generally damaged, furthermore, the damage of mitochondria and cell nucleus was especially serious. The study shed light on pathogenesis of the disease.

关 键 词：猪繁殖与呼吸综合征病毒变异株 超微结构 猪 

分 类 号：S852.3[农业科学—基础兽医学]