一点红属植物化学成分和药理作用研究进展  

Progress on Chemical Constituents and Pharmacological Activities of Genus Emilia

作　　者：沈寿茂[1] 张艳华 沈连钢[1] 雷崎方[1] 裴秋燕[1] 斯建勇[1] 

机构地区：[1]中国医学科学院北京协和医学院药用植物研究所,北京100193 [2]广西壮族自治区花红药业股份有限公司,广西柳州545007

出　　处：《中国实验方剂学杂志》2012年第12期308-312,共5页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家“重大新药创制”科技重大专项(2012ZX09301-002-001)

摘　　要：对一点红属植物的化学成分和药理作用的研究进展进行介绍,为进一步研究和开发利用提供参考。检索国内外CNKI,Mediline,CA等数据库,收集近年来有关一点红属植物的化学成分和药理作用研究的文献资料36篇,并对其进行整理、分析。一点红属植物的主要化学成分为生物碱、黄酮、挥发油等化合物,具有抗肿瘤、抗炎镇痛、抗氧化、抗糖尿病等药理作用。一点红属植物在抗肿瘤、抗炎方面有着广阔的应用前景,建议加强其物质基础研究。该属植物含有吡咯里西啶类有毒生物碱,需加强毒理学研究,为安全性用药提供依据。To review the research progress on chemical constituents and pharmacological activities of plants belonging to genus Emilia and provide useful references for the further research. The literatures and monographs about genus Emilia over the past decades were referred, and the progress of the chemical constituents and pharmacological activities were summarized. Alkaloids, flavonoids, volatile oils are the main chemical constituents of genus Emilia. Many extracts prepared from the plants of the discussed genus show various biological activities, such as anti-tumor, anti-inflammatory, anti-nociceptive, anti-oxidant, etc. Because they have wide application prospects in anti-tumor, anti-inflammatory and other aspects, the study of the substance basis of the plants of genus Emilia should be enhanced. And it is important to strengthen the research in toxicity, due to poisonous pyrrolizidine alkaloids, in order to provide references for safty.

关 键 词：一点红属 化学成分 药理作用 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]