A Case of Congenital Corneal Anesthesia with Hypopyon in China  

作　　者：Jianwen Tan Chaoran Zhang 

机构地区：[1]Department of Eye ＆ ENT Hospital of Fudan University, Shanghai 200031, China

出　　处：《Eye Science》2012年第2期106-108,共3页眼科学报（英文版）

摘　　要：Purpose:To report a case of congenital corneal anesthesia (CCA) associated with hypopyon and tactile hypoesthesia. Methods:.Case report. Results:.A 3-year-old girl presented with redness and mild photophobia in the left eye accompanied by corneal ulcer, hypopyon,.and corneal neovascularization..Corneal sensation was reduced bilaterally..She exhibited an absence of normal response to painful stimuli..She also had extensive ulceration of the lateral borders and tip of the tongue. The left corneal biopsy revealed negative cultures for bacteria and fungi. She was treated with human amniotic membrane transplantation in the left eye. The response to treatment was good. Conclusion:.This is the first case of CCA reported in China. CCA is often misdiagnosed as infectious keratitis..Amniotic membrane transplantation is effective in repairing the severe corneal ulcer which may be associated with CCA.Purpose： To report a case of congenital corneal anesthesia （CCA） associated with hypopyon and tactile hypoesthesia. Methods： Case report. Results： A 3-year-old girl presented with redness and mild photophobia in the left eye accompanied by corneal ulcer, hy- popyon, and corneal neovascularization. Corneal sensation was reduced bilaterally. She exhibited an absence of normal re- sponse to painful stimuli. She also had extensive ulceration of the lateral borders and tip of the tongue. The left corneal biop- sy revealed negative cultures for bacteria and fungi. She was treated with human amniotic membrane transplantation in the left eye. The response to treatment was good. Conclusion： This is the first case of CCA reported in China. CCA is often misdiagnosed as infectious keratitis. Amniotic membrane transplantation is effective in repairing the severe corneal ulcer which may be associated with CCA.

关 键 词：角膜炎 先天性 中国 麻醉 案例 移植治疗 羊膜移植 CCA 

分 类 号：S858.23[农业科学—临床兽医学] S858.292[农业科学—兽医学]