高血压性脑出血患者血清雌二醇的变化及临床意义  

The fluctuation and clinical significance of the serum level of estradiol in patients with Hypertensive intracerebral hemorrhage

作　　者：汪国胜[1] 钟平[1] 苏东升[1] 张雷[1] 张蕾[1] 马争飞[1] 

机构地区：[1]安徽省宿州市立医院神经内科,234000

出　　处：《蚌埠医学院学报》2012年第6期666-668,共3页Journal of Bengbu Medical College

摘　　要：目的:探讨高血压性脑出血患者雌二醇水平与病情程度及预后的相关性。方法:检测168例高血压性脑出血患者(脑出血组)及60例对照组血清雌二醇的含量,按美国国立卫生研究院卒中量表标准对患者进行评分;再按病情轻重及病程评分的差值分组比较。结果:脑出血组男女性雌二醇与对照组差异有统计学意义(P<0.01),男性不同程度脑出血和不同出血量患者雌二醇的含量差异均有统计学意义(P<0.05),而女性雌二醇的含量在病情的轻重及不同出血量间差异均无统计学意义(P>0.05);男女性好转组血清雌二醇均高于未变组及恶化组(P<0.05～P<0.01)。结论:高血压性脑出血患者血清雌二醇水平测定有助于判断预后。Objective： To investigate the fluctuation of the serum level of estradiol in patients with hypertensive intracerebral hemorrhage and the relation of the severity and prognosis of cerebral hemorrhage. Methods ： The serum level of estradiol in 168 patients and 60 healthy persons was determined. All the patients were scored by U. S. National Institutes of Health Stroke Scale（ NIHSS）, and compared in groups. Results：There was significant difference in the serum level of estradiol in patients with cerebral hemorrhage in comparison with that of controls （ P 〈 0.01 ） , there was significant difference in the serum level of estradiol and the degree of seriousness of the male patient＇s condition and the bleeding（ P 〈 0.05 ） , there was no correlation in the serum level of estradiol and the degree of seriousness of the female patient＇s condition and the bleeding（ P 〉 0.05 ）, the serum level of estradiol in the patients of the improved group was obviously higher than that of the unchanged group and the deterioration group （ P 〈 0. 05 to P 〈 0.01 ）. Conclusions： It is helpful for judging prognosis to determine the serum level of estradiol in patients with Hypertensive intraeerebral hemorrhage.

关 键 词：高血压/并发症 脑出血 雌二醇 

分 类 号：R544.1[医药卫生—心血管疾病] R743.34[医药卫生—内科学]