牡丹皮中丹皮酚提取工艺的研究  

Study of the optimum extraction process of paeonol from cortex moutan

作　　者：刘媛[1] 夏超[1] 石金城[1] 孙兴华[1] 林本青[1] 樊明[1] 

机构地区：[1]南京工业大学江苏省药物研究所,江苏南京210009

出　　处：《蚌埠医学院学报》2012年第6期725-726,729,共3页Journal of Bengbu Medical College

摘　　要：目的:研究水蒸气蒸馏法提取丹皮酚的最佳工艺。方法:以丹皮酚含量为指标,通过L9(34)正交试验法研究提取时间、加水量、药材粒度、加盐的量等工艺条件对丹皮酚提取率的影响。结果:丹皮酚的最佳提取工艺为药材粒度(0.2±0.05)cm,加6倍量水,加1%氯化钠,提取3 h。结论:水蒸气蒸馏法有效提高了牡丹皮中丹皮酚的提取含量。Objective ： To optimize the extraction process of paeonol by steam distillation. Methods： Referring to the content of paeonol, an orthogonal design table L9 （34） was used with the factors of extraction time, water-adding amount, medicinal size and salt content. Results： The optimal process of extraction was as follows ： the granularity of paeonia suffrutieosa andr was （ φ 0.2 ±0. 05 ） cm, adding 6 times amount of water, adding 1% sodium, the extraction time was 3 h. Conclusions ： Experiments show that this method is effective to improve the extraction process of Paeonol.

关 键 词：牡丹皮 丹皮酚 水蒸气蒸馏法 正交试验 

分 类 号：R965.1[医药卫生—药理学]