血小板功能与动脉粥样硬化研究进展  

Research progress on platelet function and atherosclerosis

作　　者：刘健 李群芳 匡红英[2] 刘斌 曹建平 

机构地区：[1]湖南环境职业技术学院,湖南衡阳421001 [2]南华大学附属第一医院,湖南衡阳421001

出　　处：《黑龙江医药科学》2012年第3期42-44,共3页Heilongjiang Medicine and Pharmacy

基　　金：湖南环境生物职业技术学院院长科研基金资助项目;编号:ZB2010-09

摘　　要：脂质浸润,内皮损伤,炎症侵袭,血小板聚集和活化等众多因素和机制均可促进动脉粥样硬化的发生发展。其中血小板活化以后参与动脉粥样硬化发生发展的机制尤为复杂。可能与血小板对内膜的损伤,释放出的细胞因子,以及相关脂蛋白的调节相关。Many factors and mechanisms such as lipid infiltration, endothelial damage, inflammation inva- sion, platelet aggregation and activation can promote the occurrence and development of atherosclerosis. The mechanism of platelet activation in atherosclerosis development is very complicated, which is possibly relevant to the intimal injury by platelets, release of cytokines, as well as lipoprotein regulation.

关 键 词：动脉粥样硬化 血小板 RANTES 内膜 

分 类 号：R541.4[医药卫生—心血管疾病]