众生丸生产过程影响因素探讨(二)  

Discussion(Ⅱ) of Influencing Factors in Production Process of Zhongsheng Pill

作　　者：张婕[1] 王德杭[2,1] 蒋东旭[2,1] 史岑慧[1] 谢有良[2,1] 赖小平[2,1] 

机构地区：[1]广州中医药大学,广州510006 [2]东莞广州中医药大学中医药数理工程研究院,广东东莞523808

出　　处：《中国实验方剂学杂志》2012年第13期37-39,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：广东省社会发展计划项目(2009A030100001);广东省科技计划项目(2009A030100014)

摘　　要：目的:探讨众生丸提取工艺过程中所存在的问题及解决方法。方法:采用HPLC测定众生丸提取工艺过程中咖啡酸、芍药苷、虎杖苷、黄芩苷的提取率,分析众生丸生产过程中提取工艺的影响因素。结果:黄芩、虎杖、赤芍等致密结构的根茎类药材应做必要的前处理,同时采用沸水投料是保证苷类成分提取率的重要条件。结论:研究结果中为众生丸大生产推广提供参考。Objective： To investigate problem which possibly existed in production process of Zhongsheng pill, and find solution. Method： Extraction rate of caffeic acid, paeoniflorin, polydatin and baicalin in extraction process of Zhongsheng pill were determined by HPLC, and to analyze influencing factors of extraction technology in production process of Zhongsheng pill. Result： Rhizomatous herbs with dense structure should make necessary pre-treatment, such as Scutellaria baicalensis, Polygonum cuspidatum, Paeonia lactiflora, et al. At the same time, boiling water feeding was an important condition to ensure extraction rate of glycosides. Conclusion： This study could provide reference for large-scale production of Zhongsheng pill.

关 键 词：众生丸 咖啡酸 芍药苷 虎杖苷 黄芩苷 生产过程 

分 类 号：R283.6[医药卫生—中药学]