服用抗反转录病毒药物治疗艾滋病合并贫血患者的中医症状体征特点研究  

Characteristics of TCM Symptoms among AIDS Patients with Anemia Treated with Antiretroviral Drugs

作　　者：陈秀敏[1] 刘志斌[1,2] 丁红云[1] 郭会军[1] 蒋自强[1] 

机构地区：[1]河南中医学院第一附属医院艾滋病临床研究中心,河南省郑州市450000 [2]河南中医学院

出　　处：《中国全科医学》2012年第16期1888-1890,共3页Chinese General Practice

基　　金：国家"艾滋病和病毒性肝炎等重大传染病防治"科技重大专项"十一五"计划课题(2008ZX10005-003B);国家中医药管理局中医药重点学科建设项目(国中医药发[2009]30号);郑州市科技创新团队建设项目(10CXTD140);河南省教育科学"十一五"规划2010年课题(2010-JKGHAZ-0047)

摘　　要：目的了解服用抗反转录病毒药物治疗艾滋病(AIDS)合并贫血患者的中医症状体征特点,研究其症状体征分布规律。方法通过病例回顾的方法,以国家"十一五"重大专项某课题病例资料为来源,对服用抗反转录病毒药物的AIDS合并贫血患者的中医四诊信息进行统计分析。结果共纳入121例病例,其中气血两虚证(A组)80例,脾肾阳虚证(B组)41例。A组中频率较高的症状有头晕与心悸,B组频率较高的症状有腰酸、腰膝无力、腰痛;体征中面色萎黄在A组出现频率较高,颜面浮肿、手足不温在B组频率较高,组间差异有统计学意义(P<0.05);淡红舌、痿软舌、黄苔、厚苔在A组频率较高,淡白舌、白苔、薄苔、齿痕舌在B组频率较高,组间差异无统计学意义(P>0.05)。细脉、弱脉在A组出现频率较高,沉脉、迟脉在B组出现频率较高,组间差异有统计学意义(P<0.05)。结论服用抗反转录病毒药物治疗AIDS合并贫血的患者中气血两虚证较脾肾阳虚证常见,中医四诊信息具有一定规律,需进一步开展临床研究加以明确。Objective To investigate the characteristics of symptoms and signs in traditional Chinese medicine （TCM） among acquired immunodeficiency syndrome （AIDS） patients complicated by anemia treated with antiretroviral drugs, and study the distribution feature of the symptom and signs. Methods The data came from a special subject of key researches of ＂ the 1 lth five - year plan＂ in China, and the retrospective study was conducted about information of AIDS patients with anemia treated with antiretroviral drugs collected by TCM four diagnostic methods. Results Totally 121 patients were enrolled, of which 80 belonged to qi - blood asthenia （ group A） and 41 to spleen - kidney yang deficiency （ group B）. In symptom frequency, the higher ones were dizziness and palpitation in group A, and sore waist, weakness of the waist and knees, and lumbago in group B. In sign frequency, the higher one was sallow complexion in group A, and the higher ones were facial puffiness and non - warmth of the hand and foot. All these differences between group A and group B were statistically significant （ P 〈 0.05 ）. In tongue condition, pink tongue and flaccid tongue, yellow coating and thick coating in group A ; but pale tongue, white coating, thin coating, and tooth - printed tongue in group B took the higher percentage. Nevertheless, the differences were not statistically significant （ P 〉 0. 05 ）. In pulse condition, thread pulse and weak pulse in group A, while sunken pulse and slow pulse in group B, appeared frequently （ P 〈 0.05 ） . Conclusion Qi - blood asthenia syndrome is more common than spleen - kidney yang deficiency syn- drome in AIDS patients with anemia treated by antiretroviral drugs. The information from TCM four diagnostic examinations has a certain regularity, which needs further clinical study to identify.

关 键 词：艾滋病 中医诊断 证候 舌象 脉象 

分 类 号：R512.91[医药卫生—内科学]