同种阔筋膜临床应用研究进展  

PROGRESS IN RESEARCH OF CLINICAL APPLICATIONS OF FASCIA LATA ALLOGRAFT

作　　者：董丽[1] 陈学英[1] 张育敏[1] 李宝兴[1] 王旭昇[1] 张乃丽[1] 马绍英[1] 

机构地区：[1]中国辐射防护研究院山西省医用组织库,太原030006

出　　处：《中国修复重建外科杂志》2012年第7期880-884,共5页Chinese Journal of Reparative and Reconstructive Surgery

摘　　要：目的了解近年来同种阔筋膜临床应用的研究进展。方法查阅国内外同种阔筋膜应用基础、处理技术和临床应用的相关文献,进行总结分析。结果同种阔筋膜具有细胞成分少、胶原纤维平行致密的组织学特点和免疫原性低的特点,经过不同方式处理和保存后,以细胞外基质为主要成分的支架形式供临床应用,并成功应用于眼科、泌尿外科、骨科和整形外科等领域,并已取得较为理想的治疗效果。结论同种阔筋膜作为一种天然的生物材料在临床修复缺损和功能重建中有着独特优势,随着生物医学技术的发展,有望应用于更多领域。Objective To find out the recent progress in research of clinical application of fascia lata allograft. Methods The domestic and international articles were reviewed to summarize the principal properties, processing techniques, and various uses of fascia lata allograft. Results Histologically fascia lata is composed of parallel and compact bundles of collagen fibers with few cells and immunologically it is low-antigenic. After varied tissue processing and storage techniques, fascia lata, as the scaffold only with the extracellular matrix, has been used in clinical practice and achieved good results, such as ophthalmology, urology, and orthopaedics. Conclusion Because of these unique properites in repairing defects and reconstructing functions, fascia lata allograft, as a natural biomaterial, is promising to be used in more aspects with the development of the biomedical techniques.

关 键 词：同种阔筋膜 力学强度 免疫原性 处理技术 临床应用 

分 类 号：R686[医药卫生—骨科学]