西洋参茎叶皂甙对大鼠实验性肝损伤的影响  

Effect of Saponins of Stems and Leaves of Radix Panacis Quinquefolii on Experimental liver Injury of Rats

作　　者：赵玉珍[1] 刘蕾[2] 陈立平 谭宏[1] 王淑湘[1] 

机构地区：[1]佳木斯大学基础医学院,黑龙江佳木斯154002 [2]佳木斯中心医院,黑龙江佳木斯154002

出　　处：《中成药》2000年第3期219-220,共2页Chinese Traditional Patent Medicine

摘　　要：目的:观察国产西洋参茎叶皂甙(PQS)对肝损伤的保护作用。方法:采用急性乙醇中毒大鼠模型为研究对象。结果:PQS能降低血清过氧化脂质(MDA)、血清谷丙转氨酶(SGPT)、血清谷草转氨酶(SGOT)活性,减少肝脏MDA的生成,增加肝谷胱甘肽过氧化物酶(GSHPx)活性。Objective:To observe the protective action of saponins of stem and Leaf of Radix Panacis Quinguefolii on liver injury in rats. Methods:In this study, the acute ethylism rat model was used. Results:The saponins of stem and leaf of Radix Panacis Quinguefolii could inhibit the activities of MDA, SGPT, SGOT; decrease the formation of MAD in liver; increase the activity of GSH Px. Conclusion: The saponins of stem and leaf of Radix Panacis Quinquefolii have prostective action on liver injury.

关 键 词：西洋参茎叶皂甙 大鼠 肝损伤 

分 类 号：R259.75[医药卫生—中西医结合] R285.5[医药卫生—中医内科学]