分子印迹传感器检测卡那霉素  

A Molecularly Imprinted Sensor for the Detection of Kanamycin

作　　者：廉文静[1] 邢宪荣[1] 刘素[2] 

机构地区：[1]济南大学化学化工学院,山东济南250022 [2]济南大学资源与环境学院,山东济南250022

出　　处：《济南大学学报（自然科学版）》2012年第4期348-352,共5页Journal of University of Jinan(Science and Technology)

基　　金：国家自然科学基金(31101296);山东省自然基金(ZR2010DQ025);山东省高等学校科技计划(J10LB14);济南大学博士基金(XBS1034)

摘　　要：利用分子印迹技术、结合壳聚糖-碳纳米管复合物和纳米金构建快速检测卡那霉素的分子印迹传感器。用电聚合法将分子印迹聚合物聚合到金电极上,采用循环伏安法和安培法经电化学工作站检测传感器的电流响应。结果表明:该传感器的检测线性范围为3×10-8～4×10-5mol·L-1(r=0.988),最低检测限为1.29×10-8mol.L-1(信噪比为3)。重复实验的相对标准偏差为3.6%。A molecularly imprinted sensor has been developed for the rapid detection of kanamycin by combining molecular imprinting technique, ehitosan-muhiwalled carbon nanotube composites and gold nanoparticles. The molecularly imprinted polymers （MIPs） were modified on gold eleetrodes by electropolymerization. The electrochemical behavior of the sensor was characterized by cyclic vohammetry and amperometry using an electrochemical workstation. The results show that the current response has a linear relation-ship with the concentration of kanamycin in the range of 3×10-8～4×10-5mol·L-1 （ r = 0. 988 ）, with a limit of detection （LOD） of 1.29×10-8mol.L-1 （signal to noise ratio is 3 ）. The relative standard deviation （ RSD ） of repeated experiments is 3.6%.

关 键 词：分子印迹聚合物 卡那霉素 电化学传感器 壳聚糖 

分 类 号：O657.1[理学—分析化学]