高龄不稳定性心绞痛患者血清胱抑素水平对近期预后的影响  

Impact of Serum Cystatin C Level on Short Term Prognosis in Elderly Patients with Unstable Angina

作　　者：李铁岭[1] 鲁晓春[1] 彭卫红[1] 范利[1] 

机构地区：[1]解放军总医院干部诊疗科,北京市100853

出　　处：《中国康复理论与实践》2012年第6期577-578,共2页Chinese Journal of Rehabilitation Theory and Practice

摘　　要：目的探讨血清胱抑素C(Cys C)水平与不稳定心绞痛患者近期预后的关系。方法采用散色免疫比浊法测定167例不稳定心绞痛患者血清Cys C浓度等指标,观察患者24 h内首次血清Cys C值,<1.5 mg/L者入正常组(102例),≥1.5 mg/L者入高Cys C组(65例)。记录住院期间及出院6个月内主要心血管事件、病死率和再入院率。结果高Cys C组患者心血管事件、病死率和再入院率等终点事件高于正常组(χ2=4.16,P=0.042)。结论血清Cys C水平与不稳定性心绞痛患者近期预后有密切的关系,血清CysC可作为不稳定性心绞痛患者近期心血管事件的预测因子。Objective To evaluate the impact of serum cystatin C（Cys C） level on short term prognosis in elderly patients with unstable angina（UA）.Methods 167 patients with US were involved in this study.The serum Cys C level was measured by immunonephelometric assay.The patients were divided into normal group（Cys C1.5 mg/L,n=102） and high Cys C group（Cys C≥1.5 mg/L,n=65） according to their baseline of the first Cys C level within 24 hours.The clinical outcomes,including major cardiac events,mortality and readmission during hospitalization and 6 months in the follow-up period were observed and evaluated.Results The major cardiac events,mortality and readmission rate were higher in the high Cys C group than in the normal group（χ2=4.16,P=0.042）.Conclusion The serum of Cys C level is closely related to the short term prognosis of UA,it could be a risk factor to predict major cardiac events in patients with UA.

关 键 词：不稳定性心绞痛 胱抑素C 脑钠肽 预后 

分 类 号：R541.4[医药卫生—心血管疾病]