儿童孢子丝菌病140例临床分析  

Clinical analysis of 140 cases of children sporotrichosis

作　　者：霍姗姗[1] 宋洋[1] 李珊山[1] 姚蕾[1] 刘媛媛[1] 钟淑霞[1] 田亚平[1] 于艳[1] 

机构地区：[1]吉林大学第一医院皮肤性病科,吉林长春130021

出　　处：《临床皮肤科杂志》2012年第7期403-405,共3页Journal of Clinical Dermatology

摘　　要：目的:分析总结140例儿童皮肤型孢子丝菌病病例,明确近年来儿童孢子丝菌病的临床和流行病学特点。方法:对2007年1月-2010年10月于我院皮肤科确诊的≤14岁儿童孢子丝菌病病例进行回顾性分析。结果:140例患儿中男女比例1:0.73,平均年龄5.8岁,平均病程4.59个月,冬春季节发病比率最高,但夏秋季发病并不少见。居住于农村者132例(94.29%),有外伤史者占22.86%。临床分型以固定型最常见(107例,占76.43%),其次为淋巴管型(32例,占22.86%),还有不确定型1例(占0.71%)。受累部位以面部最多(125例,占89.29%)。采用10%碘化钾溶液、伊曲康唑、特比萘芬单独或联合治疗,资料完整的患儿6个月治愈率达100%,无严重不良反应。结论:近年来儿童孢子丝菌病并不少见,累及面部和表现为固定型者较常见。采用10%碘化钾溶液、伊曲康唑及特比萘芬治疗安全有效。Objective： The aim of this research is presenting the features of children sporotrichosis in recent years by ana- lyzing the data from 140 children cases of cutaneous sporotrichosis. Methods： Retrospective analysis of children（fourteen years old or younger）sporotrichosis cases diagnosed at our clinic from Jan 2007 to Oct 2010. Results： In 140 cases, the male to female ratio was 1：0.73, the average age was 5.8 years and the average course of the disease was 4.59 months. The onset of most cases occurred in the winter and the spring while the ratio of those occurred in the summer and the autumn was not very low. The children who came from rural areas accounted for 94.29% but only 22.86% of total cases had confirmed a his- tory of trauma proor to the onset. As to the clinical types, fixed cutaneous sporotrichosis was the mostly seen （76.43%） fol- lowed by lymphocutaneous type （22.86%） and unidentified type （0.71%）. One hundred and twenty five cases（89.29%） had fa- cial involvement. Among the patients who could completely follow the instructions of doctor to finish the treatment, the cure rates after 6 months of treatment with 10% potassium iodide solution, itraconazole, terbinafine alone or the combination of these drugs were 100%, without serious adverse events. Conclusion： Children sporotrichosis cases were not rare in recent years. Facial involvement was the most common and the fixed cutaneous type was the predominant type among these patients. Potassium iodide, itraconazole and terbinafine were effective and safe treatment options.

关 键 词：孢子丝菌病 申克孢子丝菌 儿童 

分 类 号：R756.6[医药卫生—皮肤病学与性病学]