草珊瑚总黄酮对小鼠血脂的影响  

Effects of Total Flavonoids of Sarcandrae glabra on Mouse Blood-fat Content

作　　者：吉宁[1] 

机构地区：[1]贵州大学生命科学学院,贵州贵阳550025

出　　处：《山地农业生物学报》2012年第3期268-270,278,共4页Journal of Mountain Agriculture and Biology

基　　金：贵州省省地合作项目[黔科合县市科技(2009)7012-1];贵州省科技创新人才团队项目[黔科合人才团队(2010)4008]

摘　　要：通过建立小白鼠高血脂模型,提取分离草珊瑚中的总黄酮,喂食模型小白鼠,测定小白鼠血清中的甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL-C),探讨草珊瑚中的总黄酮对小鼠血脂的影响。结果表明:草珊瑚总黄酮各组小鼠血清中TG、TC、LDL-C的含量显著低于模型组(P<0.05),说明草珊瑚总黄酮有抗高血脂症的作用,高剂量降脂效果接近洛伐他丁。The total flavonoids were extracted and separated from Sarcandrae glabra, subsequently, it was used to feed the model mice of hyperlipidemia. The effect of total flavonoids on mouse blood-fat content was investigated by quantification of mouse serum triglyeeride （TG）, total cholesterol （TC）, and low dens!ty lip- oprotein（LDL-C）. The results showed that compared with the model group, treatment of total flavones gave significantly reduction in the contents of TG, TC, and LDL-C （P 〈 0.05）, indicating the total flavonoids of Sarcandrae glabra has anti-hyperlipidemia effect, ering effect to lovastatin. and use of high dosage may demonstrate the close lipid-low-

关 键 词：草珊瑚 总黄酮 高血脂 

分 类 号：R963[医药卫生—微生物与生化药学]