感觉电流阈值在糖尿病周围神经病变诊断中的临床应用  

CLINICAL APPLICATION OF CURRENT PERCEPTION THRESHOLD IN DIAGNOSIS OF DIABETIC PERIPHERAL NEUROPATHY

作　　者：田明琴[1] 李振光[1] 廖云龙[1] 黄赛平[1] 陈小玮[1] 黄康[1] 黄平[1] 

机构地区：[1]湖南省脑科医院神经电生理室,410007

出　　处：《现代电生理学杂志》2012年第2期72-75,共4页Journal of Modern Electrophysiology

摘　　要：目的:探讨感觉电流阈值(CPT)在糖尿病周围神经病变(DPN)诊断中的价值。方法:选取符合入选条件的52例2型糖尿病(T2DM)患者和50例健康人的感觉电流阈值。以神经传导速度检查(NCV)为诊断糖尿病周围神经病变的"金标准",使用χ2检验评价电流感觉阈值的灵敏度、特异度、阳性预测值、阴性预测值及Kappa值。结果:以NCV为标准,电流感觉阈值的灵敏度61.1%,特异度62.5%,阳性预测值78.6%,阴性预测值41.7%,Kappa值0.207。结论:电流感觉阈值能评估个体感觉通路功能,有助于筛查DPN患者。Objective： To discuss the value of current perception threshold in early diagnosis of diabetic peripheral neuropathy. Method： 52 random selected patients with diabetes mellitus type 2 and 100 healthy controls were measured with CPT. The nerve conducting velocity （ NCV ） detecting with electromyogram was used as standard criteria, the sensitivity, specific of CPT were analyzed. Results： Check the NCV as lty, the positive and negative predictive values and kappa values standard, the sensitivity of CPT was 61.1%, specificity was 62.5%, positive predictive value was 78.6%, negative predictive value was 41.7%, and kappa value was 0.207. Conclusion： CPT can be used to evaluate the function of sensation channel, and it is useful for screening DPN.

关 键 词：糖尿病周围神经病变 电流感觉阈值 定量感觉检查 诊断 

分 类 号：R587.2[医药卫生—内分泌]