银屑颗粒质量标准研究  

Study on the quality standard of Yinxie Granules

作　　者：李启艳[1] 游嘉[2] 徐丽华[1] 

机构地区：[1]山东省食品药品检验所,山东济南250101 [2]中山大学药学院,广东广州510006

出　　处：《齐鲁药事》2012年第6期339-340,共2页qilu pharmaceutical affairs

摘　　要：目的修订提高银屑颗粒的质量标准,并对产品进行质量考察。方法采用高效液相色谱法对银屑颗粒中落新妇苷进行含量测定;采用薄层色谱法对制剂中的菝葜进行定性鉴别。结果落新妇苷在2.67～26.7μg范围内的线性关系良好(r=0.999 9),平均回收率为98.3%(n=5);薄层色谱可明显鉴别制剂中的菝葜药材。结论建立的方法简单准确、专属性强、重现性好,能有效地控制该制剂的质量。Objective To revise and improve the quality standard of Yinxie Granules, and evaluate the quality of products. Methods The content of astilbin in Yinxie Granules was determined by HPLC ; Sarsaparilla was qualitatively identified by TLC. Results The linear range of astilbin was 2.67 - 26.7 μg（ r = 0. 999 9 ） , the average recovery was 98.3 % （ n = 5 ） ; Sarsaparilla could be identified by TLC. Conclusion The method was simple, reproducible and accurate for the quality control of Yinxie Granules.

关 键 词：银屑颗粒 质量标准 薄层色谱 高效液相色谱法 

分 类 号：R927.1[医药卫生—药学]