MIBI SPECT/CT显像在脊柱单发灶性质判定中的价值  

The value of ^(99)Tc^m-MIBI SPECT/CT imaging in differential diagnosis in single spinal lesion

作　　者：刘立水[1] 谢运周[1] 秦永德[1] 李肖红[1] 巴雅[1] 

机构地区：[1]新疆医科大学第一附属医院核医学科,乌鲁木齐830011

出　　处：《新疆医科大学学报》2012年第6期814-818,共5页Journal of Xinjiang Medical University

基　　金：新疆医科大学第一附属医院科研奖励基金(20090616)

摘　　要：目的探讨99 Tcm-MIBI SPECT/CT显像在鉴别脊柱单发灶良、恶性质中的价值。方法 76例经99 Tcm-MDP平面及融合显像发现的脊柱单发灶患者,经金标准(病理)证实的恶性55例,良性21例,均行MIBI平面显像及SPECT/CT显像。在不知病理结果的情况下进行视觉读片,结果与金标准诊断结果进行对照并行统计学处理。结果 99 Tcm-MIBI平面显像及SPECT/CT显像的灵敏度分别为81.8%和92.7%(P<0.05),特异度分别为71.4%和95.2%(P<0.05)。结论 99 Tcm-MIBI SPECT/CT显像远较其平面显像的灵敏度、特异度高,在脊柱单发灶的性质判定中有较好的临床应用价值。Objective To investigate the clinical value of 99Tcm-MIBI SPECT/CT imaging in differential diagnosis in single spinal lesion and to compare with the result of 99Tcm-MIBI planar imaging.Methods Seventy six patients（55 malignant cases and 21 benign cases） diagnosed with both 99Tcm-MIBI planar and 99Tcm-MIBI SPECT/CT imagings.Without knowing the pathology results of the visual Film,the results of statistical control in parallel with the gold standard for diagnosis.Results With seventy six cases of single skeleton lesions the sensitivity（92.7%） and specificity（95.2%） in the imaging of 99mTc-MIBI SPECT/CT were higher than the sensitivity（81.8%） and specificity（71.4%） of 99Tcm-MIBI planar imaging（P〈0.05）.Conclusion The diagnostic value in 99Tcm-MIBI SPECT/CT imaging is better than that in 99Tcm-MIBI planar imaging in the single spinal lesions.

关 键 词：脊柱单发灶 99Tcm-亚甲基二磷酸盐(99Tcm-MDP) 99Tcm-甲氧基异丁基乙腈(99Tcm-MIBI) 单光子发射计算机断层显像/计算机断层成像(SPECT/CT) 

分 类 号：R814.42[医药卫生—影像医学与核医学]