F/T比值在乳腺癌诊断和预后评估中的应用  

F/T ratio in breast cancer diagnosis and prognosis assessement of application

作　　者：王淑仙[1] 马蕾[2] 冯惠清[1] 张贺伟 

机构地区：[1]河北大学附属医院,河北保定071000 [2]保定市儿童医院,河北保定071000 [3]保定市新市区老年病医院,河北保定071000

出　　处：《医学研究与教育》2012年第3期53-55,共3页Medical Research and Education

基　　金：保定市科学技术研究与发展计划项目(11ZF039)

摘　　要：目的探讨血清游离前列腺特异性抗原(FPSA)与总前列腺特异性抗原(TPSA)比值(F/T)在女性乳腺疾病中的临床应用价值。方法用电化学发光法(ECL)检测47例乳腺癌患者、34例乳腺良性增生患者和30例正常女性的血清FPSA、TPSA,并计算F/T比值,评价其在女性乳腺疾病的诊断和预后评估价值。结果以F/T比值为0.15为判断上限时,其阳性诊断率为46.8%,明显高于TPSA和FPSA单测时的阳性诊断率。结论血清F/T比值在女性乳腺疾病诊断和预后评估方面具有重要临床应用价值。Objective To study the applied value of the ratio of the serum Free Prostate Specific Antigen（FPSA） and Total Prostate Specific Antigen（TPSA） in patients with female breast disease. Methods Electrochemiluminescence was perfomed to measure the serum FPSA and TPSA level in 47 patients of breast cancer, 34 women of benign breast diesae and 30 healthy women ;and evaluating the diagnostic and prognostic value of the ratio of the F/T to the breast disease. Results As F/T 0.15, the positive diagnosis rate was 46.8%. Its ratio was much higher than single to detect contents of FPSA or TPSA. Conclusion Detecting the ratio of F/T will be important helpful to the diagnostic and prognostic value to the breast disease.

关 键 词：电化学发光法 F/T比值 PSA水平 预后评估 乳腺癌 

分 类 号：R446[医药卫生—诊断学]