自创“四联疗法”治疗急性高原肺水肿的效果观察  

Clinical Efficacy of Self-produced Four-combination Therapy for Treating Patients with High Altitude Pulmonary Edema

作　　者：邹子扬[1] 刘俊双[1] 陈宏光[1] 赵海鹰[1] 安琳[1] 狄亮[1] 俞志军[1] 

机构地区：[1]解放军255医院内三科,河北唐山063000

出　　处：《解放军医药杂志》2012年第6期11-14,共4页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

摘　　要：目的观察自创"四联疗法"治疗急性高原肺水肿(high altitude pulmonary edema,HAPE)的疗效。方法30例患者随机分成观察组16例和对照组14例,两组均给予基础治疗,对照组给予地塞米松、氨茶碱、呋塞米治疗,观察组在对照组的基础上给予硝普钠治疗,观察两组临床疗效,症状体征、动脉血气、胸部X线改善时间和住院时间。结果两组有效率比较差异无统计学意义(P>0.05);观察组症状体征、动脉血气和胸部X线征象改善时间及住院时间均短于对照组,差异有统计学意义(P<0.05)。结论应用自创"四联疗法"在非战争军事行动中治疗HAPE安全有效。Objective To evaluate the safety and efficacy of self-produced four combination therapy for treating patients with high altitude pulmonary edema （HAPE）. Methods 30 HAPE patients were randomly divided into two groups： therapy group （n = 16） and control group （n = 14）. In addition to the basic treatment, the control group was treated with Dexamethasone, Amionphylline and Furosemide, while the therapy group was treated with these three drugs and Sodium Nitroprusside. Clinical symptoms, physical sign, arterial blood gas and X-ray shades as well as length of stay were compared. Results The difference of the two groups on efficient was no significant difference （P 〉 0.05）. Clinical symp- toms, Arterial blood gas and X-ray shades, as well as length of stay in therapy group were significantly better than those in the control group （P 〈 0.05）. Conclusion The self-produced four-combination therapy was effective and safe for manag- ing HAPE patients in peacetime military action.

关 键 词：肺水肿 高原病 治疗结果 抗震救灾 

分 类 号：R563[医药卫生—呼吸系统]