两种剂量氨甲喋呤单次肌注治疗异位妊娠  

Two dosage of single-dose intramuscular methotrexate for therapy of ectopic pregnancy

作　　者：李艳芳[1] 史秀婷[1] 迟闺珠[1] 

机构地区：[1]首都医科大学附属北京红十字朝阳医院妇产科,北京100020

出　　处：《河北医学》2000年第4期318-320,共3页Hebei Medicine

摘　　要：目的 :减少异位妊娠患者保守治疗过程中接受的氨甲喋呤剂量。 方法 :将血 HCG<50 0 0 IU/L的未破裂异位妊娠、且要求保守治疗的患者随机分为 2组 , 组单次肌注氨甲喋呤 50 mg, 组氨甲喋呤剂量按 50 mg/m2计算单次肌注 ,平均剂量为 79.17± 8、2 0 mg,并观察治疗效果。结果 :两组治疗成功率相同 ,血 HCG降到正常的时间相当。结论 :对于血 HCG<50 0 0 IU/L者可采用 50 mg氨甲喋呤单次肌注。Objective:[WT5BZ][ST5BZ]To reduce the amount of methotrexate for ectopic pregnancy.[WT5HZ]Methods:[WT5BZ]All unrupture ectopic pregnancy patients with blood HCG<5000IU/L treated with methotrexate were divided into two groups randomly.They received methotrexate 50mg or 50mg/m 2 separately.Their clinical effects were observed.[WT5HZ]Results:[WT5BZ]There were no marked differences in cure rate and the mean time from treatment initiation to resolution of the blood HCG titer.[WT5HZ]Conclusions:[WT5BZ]We can use lower dose methotrexate for therapy of ectopic pregnancy with blood HCG<5000IU/L than the dose of 50mg/m 2. [WT5HZ]

关 键 词：治疗 两种剂量 单次肌注 异位妊娠 氨甲喋呤 

分 类 号：R714.22[医药卫生—妇产科学]