保留子宫动脉全子宫切除术的临床对照研究  

Controlled Study on Efficacy of Hysterectomy with Preservation of the Uterine Artery

作　　者：陈宁[1] 孙金华[1] 喻莉莉[1] 

机构地区：[1]解放军第421医院妇产科,广东广州510000

出　　处：《中国误诊学杂志》2012年第14期3456-3458,共3页Chinese Journal of Misdiagnostics

摘　　要：目的探讨保留子宫动脉全子宫切除术对萝噤功能影响的临床价值。方法符合标准的70例全子宫切除术，按入院先后顺序（奇偶数）分成保留子宫动脉全子宫切除术35例（研究组）、常规全子宫切除术35例（对照组），观察两组手术指标、手术前后血清性激素变化、围绝经期症状的发生率和改良Kupperman评分情况。结果研究组与对照组比较，手术时间、术中出血量、术后病率差异无统计学意义，2组均无手术并发症；血清性激素（E2、FSH、LH）术前两组比较差异无统计学意义，术后6个月，研究组E明显高于对照组，FSH、LH明显低于对照组。与术前比较，研究组术后6个月E虽有降低，FSH、LH虽有所升高（3例FSH〉10IU／L），差异均元统计学意义；对照组术后6个月E2明显降低，FSH、LH明显升高，差异有统计学意义，且13例FSH〉10IU／L；1例FSH〉40IU／L，E2〈30ng／L，呈绝经期激素改变。结论保留子宫血管全子宫切除术微创、安全、可行，且较大限度地保存了子宫切除患者近期的卵巢功能。Objective To investigate the efficacy of hysterectomy with preservation of the uterine artery. Methods 70 premenopausal women with benign uterine diseases were randomly divided into tw9 groups. 35 cases received hyster- ectomy with preservation of the uterine artery in the study group,and 35 cases underwent standard hysterectomy in the control group. The ovarian function, perimenopause syndromes and modified Kupperman scores of the two groups were compared after the operations. Results There were no significant differences in operation time,intraop- erative blood loss, and postoperative morbidity. None of the patients had postoperative complications. Before the op- eration, there were no significant difference in the levels of E2, FSH, and LH between the two groups. Six months af- ter. the operation,the level of E2 in the study group was significantly higher than that in the control group, and the levels of FSH and LH in the study group were significantly lower than those in the control group. In the study group, the level of E2 decreased, and FSH and LH increased after the operation, but the changes were not significant （3 cases FSH〉 10 IU/L）. Whereas, in the control group, the level of E2 decreased significantly after the surgery while the levels of FSH and LH increased significantly（13 cases FSH〉10 IU/L; 1 case FSH〉40 IU/L and E2〈30 ng/L）. Conclusions hysterectomy with preservation of the uterine artery is safe and feasible, and preserves the o- varian function of the patients.

关 键 词：子宫切除术/方法 

分 类 号：R713.42[医药卫生—妇产科学]