高血压伴颈部动脉粥样硬化的危险性分析  

Analysis on fatalness of hypertension combined with carotid artery atherosclerosis

作　　者：叶向[1] 杨洋[1] 时霞飞 王宏俊[1] 龚元淑[2] 

机构地区：[1]江苏省南京市浦口区中心医院心内科,211800 [2]江苏省南京市浦口区中心医院心超室,211800

出　　处：《中国误诊学杂志》2012年第18期4888-4889,共2页Chinese Journal of Misdiagnostics

摘　　要：目的探讨高血压伴颈部动脉粥样硬化的危险性，及踝臂指数（ABI）、血脂Lp（a）在颈动脉粥样硬化预测中的作用。方法选取2010—01—2011—06在南京市浦口区中心医院进行住院治疗的49例高血压患者作为研究对象。同时选取同期在我院进行住院的非高血压患者50例作为对照组。测量所有研究对象的裸臂指数、血脂Lp（a）和颈动脉内膜中层厚度。结果高血压组的血脂、CRP和颈动脉厚度显著高于非高血压组，且两组差异均具有统计学意义（P〈0．05）；而ABI明显低于非高血压组，差异也具有统计学意义（P〈0．05）。ABI≤1．0与ABI〉1．0的颈动脉内膜厚度分别为（0．93±0．16）mm和（0．76±0．19）mm，差异具有统计学意义（P〈0．05），而ABI~〈1．0组的CRP显著低于ABI〉1．0组。结论ABI值和血脂Lp（a）水平与高血压具有很强的相关性，并且具有检测简便，不需要特殊设备，值得在实际工作中推广应用。Objective To investigate the fatalness of hypertensive combined with carotid artery atherosclerosis, and the effect of ankle-brachial index（ABI） and blood lipid Lp（a） in the prediction of carotid atherosclerosis. Methods 49 patients with hypertension hospitalized in our hospital from 2010 January to 2011 Junewere enrolled in the study. while 50 non-hypertensive patients were selected hospitalized in our hospital as control group. Brachial index, blood lipid Lp（a） and carotid intima media thickness of all subjects were measured. Results The blood lipids and thickness of the carotid artery of hypertensive group were significantly higher than the non-hypertensive group, and the differ- ence between two groups were statistically significant（ P〈0. 05 ） ;and ABi significantly lower than non-hypertensive group, the difference was statistically significant（P〈（0.05）. The carotid artery intima-media thickness of ABI≤ 1.0 and ABI〉I. 0 group was（0. 93±0.16） mm and （0. 76±0.19） mm respectively. The difference was statistically significant（P〈0.05） ,indicating the correlation between lower ABI and carotid atherosclerosis. Conclusion There are strong correlation between ABI values,lipid Lp（a） levels and hypertension. The test is simple and does not require special equipment, and it is worth applicate widely in clinical practice.

关 键 词：高血压/并发症 颈动脉疾病/并发症 

分 类 号：R544.1[医药卫生—心血管疾病] R543.5[医药卫生—内科学]