溶栓治疗对急性心肌梗死患者运动耐量的影响  

Effects of thrombolytic therapy on exercise tolerance of patients with acute myocardial infarction

作　　者：石理 兰曦 李军 朱卫民 林佩君 彭健 

机构地区：[1]珠海市人民医院心内科,广东珠海519000

出　　处：《临床心血管病杂志》2000年第4期154-155,共2页Journal of Clinical Cardiology

摘　　要：目的 :探讨溶栓治疗对急性心肌梗死 (AMI)患者急性期和远期运动耐量的影响。方法 :将 143例 AMI患者分为溶栓再通组 (35例 )、未通组 (2 3例 )和非溶栓组 (85例 ) ,比较三组急性期和远期运动耐量。结果 :急性期 ,再通组的运动量、运动时间、最大心率、心率血压乘积均明显高于未通组和非溶栓组 (P<0 .0 5 ) ,运动诱发的心绞痛或血压下降≥ 10 m m Hg(1m m Hg=0 .133k Pa)的比率明显低于后两者 (P <0 .0 5 )。远期随访 ,三组的运动量、最大心率、运动时间、心率血压乘积及运动诱发心绞痛或血压下降的比率均无显著性差异 (P >0 .0 5 )。结论 :溶栓再通能显著提高 AMI患者急性期运动耐量 。Objective:To study the effects of thrombolytic therapy on exercise tolerance of patients with acute myocardial infarction (AMI).Method:143 AMI patients were divided into thrombolysis with patency group (35 cases), thrombolysis with non-patency group(23 cases) and non-thrombolysis group(85 cases). Exercise tolerance of all patients in three groups was analysed and compared.Result:① In acute outcome, exercise time, maximal heart rate and rate-pressure product in patency group were much better than the non-patency group and non-thrombolysis group(P< 0.05 ), exercise-induced angina pectoris or SBP drop≥ 10 mmHg in patency were much lower than the other groups(P< 0.05 ). ②In long-term follow-up,the incidence of exercise-induced angina pectoris or SBP dropped≥10 mmHg , exercise time , maximal heart rate and rate-pressure product had no significant difference among the three groups(P> 0.05 ).Conclusion:Thrombolytic patency could improve exercise tolerance of patients with AMI in the acute outcome, but could not improve the exercise tolerance in long-term follow-up.

关 键 词：急性 心肌梗塞 溶栓疗法 运动耐量 

分 类 号：R542.22[医药卫生—心血管疾病]