无机三氧化聚合物的研究进展与临床应用  

Research progress and clinical application of mineral trioxide aggregate

作　　者：朱兰兰[1] 王秀梅[1] 

机构地区：[1]哈尔滨医科大学附属第二医院口腔科,黑龙江省哈尔滨市150001

出　　处：《中国组织工程研究》2012年第25期4692-4696,共5页Chinese Journal of Tissue Engineering Research

基　　金：黑龙江省自然科学基金项目(D201175);黑龙江省政府博士后启动基金资助(LRB05-279)~~

摘　　要：背景:近年来国内外出现一种新型牙髓病修复材料——无机三氧化聚合物,由于它具有良好的理化性质及生物相容性,已经被广泛研究并应用于临床治疗牙髓病。目的:从理化性质、封闭性、生物相容性、生物活性和临床应用等方面综述无机三氧化聚合物的研究进展。方法:应用计算机检索CNKI与Pubmed数据库中1993-01/2011-12关于无机三氧化聚合物的文章,在标题和摘要中以"无机三氧化聚合物;盖髓材料;牙髓病治疗"或"Mineral trioxide aggregate,capping material,endodontic treatment"为检索词进行检索。选择文章内容与无机三氧化聚合物有关者,同一领域文献则选择近期发表或发表在权威杂志文章。初检得到68篇文献。根据纳入标准选择关于无机三氧化聚合物的40篇文献进行综述。结果与结论:无机三氧化聚合物的应用对临床上一些牙髓疾病的治疗起到很好的辅助作用,以理化性质优良,封闭性、生物相容性与生物活性良好等特点被广泛关注,尤其随着牙髓病相关药物及材料的研究,其在口腔临床治疗中的应用必将更加广泛。BACKGROUND： In recent years, a new-type dental material, mineral trioxide aggregate （MTA） emerges at home and aboard. It is widely used in clinical application because of its good physical and chemical properties and perfect biocompatibility. OBJECTIVE： To review the physical and chemical properties, biocompatibility and clinical application of MTA. METHODS： A computer-based research was performed on CNKI database and PubMed database （1993 01/2011 12） to search the related articles about MTA. The key words were ＂mineral trioxide aggregate, capping material, endodontic treatment＂ in English and Chinese. The related articles were selected. There are 68 articles after the initial survey. Then selecting 40 articles related MTA were concluded to review according to the conclusion criteria. RESULTS AND CONCLUSION： Application of MTA is a well adjuvant therapy for some special clinical pulposis. And it has attracted a wide spread attention by its good physical and chemical properties, closure property, biological activity and biological compatibility. The clinical application of MTA will be widely used along with the development of medicine and materials.

关 键 词：无机三氧化聚合物 盖髓材料 牙髓病治疗 直接盖髓 间接盖髓 生物材料 

分 类 号：R318[医药卫生—生物医学工程]