早期气管插管行机械通气在急性重症左心衰竭抢救中的价值  

Evaluation of early trachea cannula mechanical ventilation as a treatment of severe acute left ventricular failures

作　　者：肖军[1] 王洪叶[1] 王德水[1] 张伟[1] 陶耀兵[1] 杨爽[1] 

机构地区：[1]解放军309医院心内科,北京100091

出　　处：《中华保健医学杂志》2012年第3期203-205,共3页Chinese Journal of Health Care and Medicine

摘　　要：目的评价早期气管插管行机械通气在急性重症左心衰竭抢救中的价值。方法根据是否早期应用气管插管行机械通气将112例急性重症左心衰竭患者分为早期机械通气组(36例)和常规机械通气组(76例),比较2组患者血脑钠尿肽值、症状缓解时间、机械通气时间、住院时间及病死率。结果与常规机械通气组比较,早期机械通气组症状缓解时间快[(4.3±1.1)h vs(7.3±2.1)h,P<0.01)],机械通气时间短[(66.4±12.4)h vs(78.3±15.6)h,P<0.01)],入院7d血脑钠尿肽浓度低[(452±112)ng/L vs(634±232)ng/L,P<0.01)],住院时间短[(15.3±5.1)d vs(21.1±7.1)d,P<0.01)],住院期间病死率低(8.3%vs 27.6%,P<0.05)。结论早期气管插管行机械通气治疗,能较快缓解急性重症左心衰竭患者的临床症状,减少机械通气时间,缩短住院时间,减少住院期间病死率。Objective To evaluate the effectiveness of early trachea eannula mechanical ventilation in treating severe acute left ventrieular failures. Methods One hundred and twelve patients with severe acute left ventricular failures were divided into two groups：early mechanical ventilation group （n=36）and conventional mechanical ventilation group （n=76）. The time of symptomatic relief,duration of mechanical ventilation,blood-brain natriuretie peptide（BNP）,inpatient time and hospital mortality of the two groups were compared. Results Compared with conventional mechanical ventilation group,early mechanical ventilation group＇s time of symptomatic relief decreased significantly[ （4.3±1.1）h vs （7.3±2.1）h ,P〈0.011 ;its duration of mechanical ventilation[ （66.4±12.4）h vs （78.3 ±15.6）h,P〈0.01]and BNP concentration [（452 ＋ll2）ng/L vs （634±232）ng/L,P〈0.011also decreased. 7 days after hospitalization ,early mechanical ventilation group＇s inpatient time t （15.3±5.1）d vs （21.1 ±7.1 ）d ,P〈0.01 ]and hospital mortality （8.3% vs 27.6% ,P〈0.05）both deereased. Conclusions Early trachea cannula mechanical ventilation can decrease the time of symptomatic relief, duration of mechanical ventilation, inpatient time and hospital mortality of the patients with severe acute left ventrieular failure.

关 键 词：急性左心衰竭 机械通气 气管插管 

分 类 号：R541.6[医药卫生—心血管疾病]