普外科Ⅰ类切口手术围术期抗菌药物使用分析  

Analysis of perioperative antibiotics use in type I incision operation of general surgery

作　　者：孙丽[1] 刘金英[1] 魏旭[1] 王宾[1] 

机构地区：[1]广州医学院附属深圳沙井医院药剂科,广东深圳518104

出　　处：《中国医药导报》2012年第18期129-131,共3页China Medical Herald

摘　　要：目的探讨普外科Ⅰ类切口手术围术期抗菌药物的应用现状及合理性。方法随机抽查2011年7~12月我院普外科300例Ⅰ类切口手术病历,统计分析围术期预防性抗菌药物使用情况。结果普外科Ⅰ类切口手术抗菌药物预防性应用率为100.00%;单一或二联用药率分别为91.67%和8.33%;预防使用抗菌药物涉及5类12个品种;抗菌药物使用频度居前3位的依次为头孢孟多（51例次）、头孢呋辛（49例次）和头孢西丁（48例次）;91.33%的患者于术前0.5~2 h给药,术后抗菌药物预防使用时间大于48 h者占32.66%。结论普外科Ⅰ类切口手术预防性用药存在用药指征把握不严、药物品种选择不当、用药时机不当及术后用药时间过长等严重的不合理现象。Objective To explore application status and rationality of perioperative antibiotics usage in type I incision op- eration of general surgery. Methods 300 general surgical medical records of type Ⅰ incision operation in our hospital from July to December 2011 were randomly collected. The condition of perioperative prophylactic antibiotic usage was analyzed statistically. Results All patients （100.00%） underwent type I incision operation were received prophylactic antibiotic in general surgery. Single and combination usage rate of antibiotics were 91.67% and 8.33% respectively. Antibiotics used for prevention included 5 categories and 12 kinds. The top 3 antimicrobial agents on the DDDs list were Cefamandole （51 cases）, Cefuroxime （49 cases） and Cefoxitin （48 cases）. Among 300 cases, 91.33% used antibiotics within 0.5-2 hours be- fore operation, and 32.66% used antibiotics more than 48 hours after operation. Conclusion There are severely unreason- able phenomenon of preventive antibiotics use in type Ⅰ incision operation of general surgery, especially including of medic- inal indication improper grasp, incorrect choice of drugs, inappropriate administration occasion and prolonged postoperative use of antimicrobials.

关 键 词：普外科 围术期 抗菌药物 合理性 

分 类 号：R978.1[医药卫生—药品]