不同治疗方法对新生儿缺氧缺血性脑病预后的影响  

The Impact of Different Treatments on the Prognosis of Neonatal Hypoxic-ischemic Encephalopathy

作　　者：谭丁丁[1] 

机构地区：[1]广东省东莞市太平人民医院,广东东莞523905

出　　处：《临床医学工程》2012年第6期941-942,共2页Clinical Medicine & Engineering

摘　　要：目的观察不同治疗方法对新生儿缺氧缺血性脑病(HIE)预后的影响。方法将我院2009年9月至2011年9月收治的200例新生儿缺氧缺血性脑病患儿随机分为观察组和对照组各100例。观察组采用施捷因治疗,对照组采用胞二磷胆碱治疗,比较两组患儿行为神经评分、临床症状恢复时间、药物副作用情况,以此来判定药物的预后影响。结果胞二磷胆碱和施捷因治疗新生儿缺氧缺血性脑病临床疗效相当,但施捷因治疗副作用少。结论施捷因治疗新生儿缺氧缺血性脑病疗效好,副作用小,值得临床推广应用。Objective To observe the impact of different treatments on the prognosis of neonatal hypoxic-ischemic encephalopathy. Methods 200 children with neonatal hypoxic-ischemic encephalopathy in our hospital from September 2009 to September 2011 were selected and randomly divided into the observation group and the control group with 100 cases in each group. 100 cases of the observation group received shijieyin for treatment, while 100 cases of the control group received citicoline for treatment. The behavioral neurological assessment, recovery time of clinical symptoms, adverse drug reactions were compared to determine the prognostic impact of the drug. Results The clinical effects of citicoline and shijieyin for neonatal hypoxic-ischemic encephalopathy were similar, but the treatment of shijieyin had fewer side effects. Conclusions Shijieyin has better effects and fewer side effects in the treatment of neonatal hypoxic-ischemic encephalopathy, which is worthy of clinical application.

关 键 词：新生儿缺氧缺血性脑病 胞二磷胆碱 施捷因 预后 

分 类 号：R722.19[医药卫生—儿科]