米非司酮配伍卡前列甲酯栓用于中期引产的临床观察  

Clinical observation of Carprost combined with mifepristone in trimester pregnancy

作　　者：于俊岭[1] 

机构地区：[1]河北省河间市人民医院,062450

出　　处：《临床合理用药杂志》2012年第17期13-14,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的探讨米非司酮配伍卡前列甲酯栓(卡孕栓)终止中期妊娠(孕13～24周)的临床疗效。方法将116例要求终止妊娠的中期妊娠孕妇随机分为观察组和对照组各58例。观察组予以米非司酮配伍卡孕栓引产,对照组予以乳酸依沙吖啶注射液引产。对2组引产效果及引产情况进行比较。结果观察组完全流产率为84.48%,高于对照组的72.41%;总产程短于对照组,产时及产后2h出血量少于对照组,差异均有统计学意义(P<0.05)。2组用药引产时间比较差异无统计学意义(P>0.05)。结论米非司酮配伍卡孕栓是一种方便、经济、安全、有效的引产方法,值得临床推广应用。Objective To explore clinical efficacy of Carprost combined with mifepristone trimester pregnancy（ 13 24 weeks）. Methods 116 cases of termination of pregnancy were randomly divided into the observation group and the control group with 58 cases in each group. The observation group to mifepristone in combination with carboprost suppositories for in- duction of labor, and control group was treated with ethacridine lactate injection induced labor. Effect of induced abortion and induced abortion of 2 groups were compared. Results The complete abortion rate in observation group was 84.48% , higher than that of control group 72.41% ;the birth process was shorter than the control group, intrapartum and postpartum bleeding volume in 2hours was decreased than those in the control group, and the difference was statistically significant （ P 〈 0.05 ）. But induction labor time showed no significant difference （ P 〉 0.05 ）. Conclusion Mifepristone and Carprost is a convenient, economical, safe, effective method of induction of labor and it is should be introduced.

关 键 词：卡孕栓 米非司酮 乳酸依沙吖啶 中期引产 

分 类 号：R719.31[医药卫生—妇产科学]