三烃基锡二茂铁甲酸酯的合成、表征及其生物活性  

Synthesis, Characterization and Biological Activities of Trialkyltin(Ⅳ) Ferrocene Carboxylates

作　　者：罗宁[1] 孙丽娟[2] 刘治中[1] 谢庆兰[2] 母昭德[3] 

机构地区：[1]后勤工程学院油品应用化学系 [2]南开大学元素有机化学研究所,天津300071 [3]重庆医科大学基础医学院

出　　处：《应用化学》2000年第2期154-158,共5页Chinese Journal of Applied Chemistry

摘　　要：合成了 13种三烃基锡二茂铁甲酸酯类化合物 ,对化合物进行了元素分析和谱学表征 .化合物生物活性测定表明 ,其生物选择性主要取决于锡原子上的 3个烃基 ,其中含有环己基、丁基、甲基和 RMe2 Si CH2 基的衍生物具有较好的杀螨活性 。Thirteen trialkyltin(Ⅳ) ferrocene carboxylates were synthesized. Their compositions and structures were characterized by UV, IR, 1H NMR and elemental analysis. The bioassay tests showed that the bioactivity selectivity of the compounds was in close relation with the substituents on the Sn atom. The compounds having cyclohexyl, butyl, methyl and RMeSiCH 2(R=Me,Et) on the Sn atom exhibited an excellent acaricidal activity and among them the tributyltin ferrocene carboxylate appeared to be the most fungicidal active.

关 键 词：三烃基二茂铁甲酸酯 合成 谱学表征 生物活性 

分 类 号：O627.42[理学—有机化学] O627.81[理学—化学]