D5和D6冻融囊胚移植的比较  

A comparison of day 5 and day 6 frozon-thawed blastocyst transfers

作　　者：刘吉[1] 胡煜[1] 宫立国[1] 翁宁[1] 许篷 程东凯[1] 于洪君[1] 孙晓玲[1] 李宝山[1] 

机构地区：[1]沈阳东方医疗集团菁华医院,沈阳110005

出　　处：《中国优生与遗传杂志》2012年第6期108-109,111,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的分析D5和D6冻融囊胚移植的结局。方法 D5和D6囊胚利用玻璃化冷冻法分别冷冻,待患者子宫内膜达到7～8mm时,以第5天为移植窗,复苏2h后移植。结果 D5冷冻囊胚复苏后的存活率(99.02%)与D6冷冻囊胚复苏后的存活率(98.51%)没有差异,D5冻融囊胚移植的临床妊娠率(62.20%)和种植率(40.69%)略高于D6冻融囊胚移植的临床妊娠率(57.40%)和种植率(36.87%),但没有显著差异,而D6冻融囊胚移植后的流产率(18.75%)显著高于D5(10.77%)(P<0.05)。结论 D5冻融囊胚移植能够提高新生儿出生率。Objective： To analyze cycle outcome among Day 5 and Day 6 cryopreserved frozen-thawed blastocyst transfers.Methods： Blastocysts of Day 5 and Day 6 were cryopreserved respectively.The surviving blastocysts cultured for over 2h after warning were transferred into the patient＇s uterus when endometrial thickness was 7~8mm and the transplanting window was Day5.Results： There was no significant difference in post-thaw survival rate of blastocysts frozen Day 5（99.02%） compared with blastocysts frozen Day 6（98.51%）.The clinical pregnancy rate（62.20%） and implantation rate（40.69%） of Day 5 frozen-thawed blastocyst were higher than clinical pregnancy rate（57.40%） and implantation rate（36.87%） of Day 6 slightly,no significant difference.However,the abortion rate（18.75%） of Day 6 frezon-thawed blastocyst transfer was higher than the abortion rate（10.77%）of D5（P0.05）.Conclusion： D5 frezon-thawed blastocyst transfer can improve live birth rates.

关 键 词：囊胚 冷冻保存 冻融 移植 妊娠率 

分 类 号：R714.8[医药卫生—妇产科学]