Identification of dimethylamphetamine in a suspect exhibit  

可疑检材中二甲基安非他明的确证分析(英文)

作　　者：徐鹏[1,2] 林文斯[1] 朱传钧[3] 刘克林[2] 常颖[2] 崔育新[1] 凌笑梅[1] 卢炜[1] 

机构地区：[1]北京大学医学部药学院,北京100191 [2]公安部物证鉴定中心,北京100038 [3]中国科学院上海有机化学研究所,上海201512

出　　处：《Journal of Chinese Pharmaceutical Sciences》2012年第4期355-359,共5页中国药学（英文版）

基　　金：National Technology Support Project Foundation China (Grant No. 2011BAK04B03)

摘　　要：N,N-Dimethylamphetamine （DMA） is a methamphetamine （MA） analog and considered as an amphetamine-derived designer drug. In this study, a method of gas chromatography-mass spectrometry （GC-MS） combined with nuclear magnetic resonance spectroscopy （1H and 13C NMR） was developed for the identification of dimethylamphetamine in a suspect exhibit. The results showed that purity of this sample was above 99% by GC-MS area normalization. Therefore, it could be used as a dimethylamphetamine reference substance in drug FTIR analysis, which was successfully applied to identify samples in other similar cases.对缴获的白色可疑晶体样品进行主要有机成分的检验。采用GC-MS和NMR分析的方法对其进行定性分析。白色可疑晶体样品中的主要有机成分为二甲基安非他明且纯度大于99%。该样品在毒品红外分析时可用作二甲基安非他明的对照品, 并成功应用于其他类似案件中检材的定性分析。

关 键 词：White crystal Dimethylamphetamine GC-MS NMR FTIR 

分 类 号：D919.1[医药卫生—法医学]