慢性乙肝病毒感染与抗磷脂抗体的关系  

Prevalence of Anti-phospholipid Autoantibodi in patients with Chronic Hepatitis B Virus Infection

作　　者：高普均[1] 曲立科[2] 时彤[2] 杨翰仪[2] 

机构地区：[1]白求恩医科大学第一临床学院消化科,长春130021 [2]白求恩医科大学基础医学院生物化学教研室,长春130021

出　　处：《临床肝胆病杂志》2000年第2期99-100,共2页Journal of Clinical Hepatology

摘　　要：探讨慢性乙肝病毒 (HBV)感染与抗磷脂抗体 (APA)水平的相关性 ;采用ELISA方法 ,检测慢性乙型肝炎及乙肝后肝硬化患者血清中APA的水平 ;与对照组相比 ,患者血清中APA均有显著升高 (P <0 0 5 ) ,且两组患者间亦有显著差异 (P <0 0 5 ) ;WT5”BZ]Antiphospholipid antibodies(APAs) have been reported in various clinical conditions The objective of the present study was to assess the prevalence of APAs in patients with chronic hepatitis B virus related liver diseases 32 healthy subject,27 patients with chronic hepatitis B and 36 patients with liver cirrhosis after hepatitis B were assayed for serum APA level by ELISA Compared with healthy subjects,two groups of patients show increased APA positive rate(37% vs 3% and 36% vs 3% respectively,P<0 05) As for the APA levels both groups of patients manifested significant increased APA levels(0 3653±0 142 vs 0 2140±0 094 of hepatitis B group and 0 4430±0 127 vs 0 2140±0 094 of cirrhosis group <0 05) Thus,this study indicate APA is associated with chronic liver disease realted HBV infection [WT5”HZ]

关 键 词：慢性乙型肝炎 病毒感染 抗磷脂抗体 

分 类 号：R373.21[医药卫生—病原生物学]