鸡冠花对小鼠耐力影响的实验研究  

Experimental Research of Celosia Cristata L on the Mouse Endurance

作　　者：陈静 李坦 姜秀梅 韩冬 

机构地区：[1]北华大学医学院预防医学系,吉林市132001 [2]吉林市卫生防疫站

出　　处：《预防医学文献信息》2000年第2期109-110,共2页Liferatue and Information On Preventine Medicine

基　　金：吉林省教委科研基金

摘　　要：[目的 ]探讨鸡冠花对小鼠机体耐受力的影响。 [方法 ]用随机数字表法将小鼠分成耐缺氧、耐高温、游泳 3大实验组 ,每大组又随机分为高、低剂量和对照 3小组 ,每小组 14只 ,雌雄各半。高、低剂量组按 2 5 g kg、1 2 5g kg用鸡冠花液灌胃 ,1次 d ;对照组用蒸馏水同量灌胃 ,2 5d后进行实验 ,并测定其肌糖原肝糖原含量。 [结果 ]高剂量组耐缺氧、耐高温、游泳实验时间 (min)分别为 44 42± 14 5 6、40 42± 17 0 1、90 5 8± 2 0 49,低剂量组分别为 3 9 5 0± 10 11、3 8 67±12 5 6、76 67± 2 1 96,对照组分别为 3 4 0 0± 8 41、3 8 2 5± 12 42、64 47± 8 79;高剂量组耐缺氧、耐高温、游泳实验肌糖原和肝糖原含量 (mg 10 0 g组织 )分别为 0 95± 0 2 8和 2 14± 0 5 8、1 17± 0 2 6和 1 78± 0 47、1 19± 1 0 3和 1 10±0 3 9,低剂量组分别为 0 84± 0 2 6和 1 5 2± 0 2 8、1 0 2± 0 2 3和 1 15± 0 13、0 76± 0 17和 1 0 3± 0 76,对照组分别为 0 44± 0 13和 1 14± 0 70、0 82± 0 15和 1 15± 0 19、0 47± 0 2 0和 1 0 0± 0 43。 [结论 ]鸡冠花具有增强小鼠耐受力和增加小鼠肌糖原、肝糖原储备的作用。Objective]To examine the effect of Celosia Cristata L on the mouse endurance.[Methods]The mice were divided randomly into anoxia-resistance, high temperature-resistance and swimming groups, and each group has low dose, high dose and control subgroups. Each subgroup has 14 mice with female and male equally. In the drug-treatde subgroups, Celosia Cristata L was administrated orally to mice, 1 25g/kg for low dose and 2 5g/kg for high dose, one time daily. In the control group, distilled water was administrated. After 25 days, the contents of muscle glycogen and liver starch of the mice were assayed.[Results]The surviving time (min) in high dose subgroups of anoxia-resistance, high temperature-resistance and swimming groups were44 42±14 56,40 42±17 01 and 90 58±20 49; in the low dose subgroups,39 50±10 11,38 67±12 56 and 76 67±21 96 respectively; in the control subgroups,34 00±8 41,38 25±12 42 and 64 47±8 79 respectively. The contents (mg/100g) of muscle glycogen and liver starch in high dose subgroups were 0 95±0 28 and 2 14±0 58,1 17±0 26 and 1 78±0 47,1 19±1 03 and 1 10±0 39 respectively; in low dose subgroups, 0 84±0 26 and 1 52±0 28,1 02±0 23 and 1 15±0 13,0 76±0 17 and 1 03±0 76 respectively; in the control subgroups, 0 44±0 13 and 1 14±0 70,0 82±0 15 and 1 15±0 19,0 47±0 20 and 1 00±0 43.[Conclusion]This experiment suggested that Celosia Cristata L could strengthen the mouse endurance and increase the deposit of muscle glycogen and liver statch.

关 键 词：鸡冠花 小鼠 耐受力 

分 类 号：R285.5[医药卫生—中药学]