冠心病患者血清脂蛋白(a)与氧化低密度脂蛋白水平的临床研究  

Clinical research of lipoprotein(a) and oxidized low-density lipoprotein level in coronary heart disease patients

作　　者：张守龙 

机构地区：[1]山东省淄博市张店区人民医院心内科,山东淄博255000

出　　处：《中国现代医生》2012年第16期56-57,共2页China Modern Doctor

摘　　要：目的探讨冠心病患者血清脂蛋白(a)与氧化低密度脂蛋白水平的变化及临床价值。方法选取我院收治的冠心病患者65例作为研究对象,另选择健康体检者25例作为对照组,分别测定两组患者血清脂蛋白(a)[Lp(a)]、氧化低密度脂蛋白(ox-LDL)及其他血脂指标,并对检测结果进行分析。结果冠心病各临床类型患者血清Lp(a)和ox-LDL水平均显著高于正常对照组,组间比较差异有统计学意义(P<0.05或<0.01)。结论冠心病患者血清Lp(a)和ox-LDL水平均明显升高,联合检测脂蛋白(a)及ox-LDL对预测冠心病的发生具有重要意义。Objective To investigate the changes of lipoprotein （a） and oxidized low-density lipoprotein level in coronary heart disease patients and their clinical value. Methods Selected 65 coronary heart disease patients in our hospital as research objects, and the other 25 cases were selected as healthy control group, serum lipoprotein （a） [Lp （a）], oxidized low-density lipoprotein protein （ox-LDL） and other lipid levels were measured in both groups, and the results were analyzed. Results Lp（a） and ox-LDL level in various clinical types of CHD group were significantly higher than the control group （P 〈 0.05 or 〈 0.01）. Conclusion Lp （a） and ox-LDL levels of coronary heart disease patients were significantly increased, the com- bined detection of lipoprotein （a） and ox-LDL is important to predict the incidence of coronary heart disease.

关 键 词：冠心病 脂蛋白(a) 氧化低密度脂蛋白 

分 类 号：R541.4[医药卫生—心血管疾病]