慢性充血性心力衰竭患者血清肌钙蛋白T的变化及意义  

Changes and Significace of Serum cTn T in Patients with Chronic Congestive Heart Failure

作　　者：陶志刚[1] 王洪敏[1] 李如臻[1] 刘运祥[1] 吴金英[1] 梁亚风[1] 

机构地区：[1]烟台毓璜顶医院,264000

出　　处：《山东医药》2000年第7期14-15,共2页Shandong Medical Journal

摘　　要：采用 ELISA法测定 77例慢性充血性心力衰竭 (心衰 )患者和 2 0例健康人的血清心肌肌钙蛋白 T(c Tn- T)。结果显示 ,轻中度心衰患者血清 c Tn- T与健康人无显著差异 (P>0 .0 5) ,重度心衰患者明显高于健康人和轻中度心衰者 (P<0 .0 1) ,冠心病与非冠心病重度心衰患者无显著差异 (P>0 .0 5)。提示不同病因的重度心衰患者均有心肌细胞损伤 ,促使损伤心肌修复是治疗心衰的重要组成部分。The Serum cardiac troponin T(cTn T)were measured in 77 patients with chronic heart failure and 20 healthy persons by ELISA method Results Showed that there was no significant difference in serum cTn T between patients with milld,moderate heart failure and healthy persons(P>0 05) Serum cTn T in patients with severe heart failure was higher significantly than those with mild and moderate heart failure as well as healthy persons(P<0 01 respectively) In patients with severe heart failure,there was no significant difference in serum cTn T in coronary heart disease compared with other heart diseases(P>0 05) This indicates that there is obvious myocardial cellular damage in all of severe heart failure caused by different heart diseases It is important to repair the damaged myocardial cells for treatment of heart failure

关 键 词：充血性心力衰竭 心肌肌钙蛋白T cTn-T 

分 类 号：R541.610.2[医药卫生—心血管疾病]