微波辐射下一步合成4-芳基-2,6-二(3,3＇-香豆素基)吡啶衍生物  

One-Pot Synthesis of 3,3'-(4-Arylpyridine-2,6-diyl)bis(2H-chromen-2-one) Derviatives under Microwave Irradiation

作　　者：周建峰[1] 娄风文[1] 孙小军[1] 安礼涛[1] 支三军[1] 霍娟娟[1] 郑丽[1] 王星帅[1] 

机构地区：[1]淮阴师范学院化学化工学院、江苏省低维材料化学重点建设实验室,淮安223300

出　　处：《有机化学》2012年第6期1112-1115,共4页Chinese Journal of Organic Chemistry

基　　金：江苏省低维材料化学重点建设实验室开放基金(No.JSKC11101)资助项目~~

摘　　要：3-乙酰基香豆素、芳醛和醋酸铵在醋酸溶剂中经微波辐射,一步合成了4-芳基-2,6-二(3,3'-香豆素基)吡啶衍生物,反应在5～8 min内完成,产率60%～86%,具有反应时间短、操作简便和环境友好等优点.所以产物经红外光谱、氢谱、质谱和元素分析表征.A series of 3,3＇-（4-arylpyridine-2,6-diyl）bis（2H-chromen-2-one） derviatives were synthesized by the one-pot reaction time,easy work-up and environmental begin.Their structures were confirmed by 1H NMR,IR,MS techniques and three-component reaction of 3-acetyl coumarin,aromatic aldehydes,and ammonium acetate in acetic acid under microwave irradiation.The reactions were completed in 5～8 min with 60%～86% yields,and the procedure has the advantages of short elemental analysis.

关 键 词：3-乙酰基香豆素 芳醛 吡啶衍生物 微波辐射 

分 类 号：O626.32[理学—有机化学]