踝臂指数与冠状动脉狭窄程度的关系  

The relationship between ankle-brachial index and the extent of coronary atherosclerosis lesions

作　　者：张茵[1] 卞瑾[1] 孙羽[1] 宋颖[1] 吴亚杰[1] 陈伊[1] 冯新星[1] 王怡璐[2] 高硕[2] 王继征[2] 邹玉宝[1] 宋雷[1] 袁晋青[1] 惠汝太 孙凯[2] 

机构地区：[1]中国医学科学院,北京协和医学院,国家心血管病中心,阜外心血管病医院心内科,北京市100037 [2]中国医学科学院,北京协和医学院,国家心血管病中心,阜外心血管病医院心血管疾病国家重点实验室,北京市100037

出　　处：《中国分子心脏病学杂志》2012年第3期140-142,共3页Molecular Cardiology of China

基　　金：国家重大基础项目(2010CB732601)

摘　　要：目的探讨踝臂指数与冠状动脉狭窄程度的关系。方法入选在我院住院的837例患者,其中男553例,女284例,平均年龄59.31±9.85岁.行冠造动脉造影术,以Gensini评分评价患者冠状动脉狭窄程度,检测ABI,以ABI≤0.9作为诊断外周血管病的标准。结果 ABI的高低与冠脉狭窄程度显著相关,随着ABI值的降低,Gensini评分会增加,两者呈负相关关系。同时,ABI值与动脉粥样硬化累积的冠脉支数也相关,伴有PAD冠心病患者的较外周血管正常的患者,三支病变和左主干病变所占的比例高。结论 ABI可作为冠状动脉粥样硬化的生物标记,能够反映冠状动脉狭窄程度。Objective To determine the relation between ankle-brachial index（ABI） and extent of coronary atherosclerosis.Methods In this cross-sectional descriptive-analytic research,837 patients with suspected CAD were investigated.Characteristics of studied subjects including demographics,familial history,past medical history and atherosclerotic risk factors such as diabetes mellitus,hypertension,hyperlipidemia and smoking were obtained using a standard questionnaire.ABI was measured in all studied patients.ABI ≤ 0.9 was considered as peripheral vessel disease and ABI 0.9 was considered as normal.Then,all studied patients underwent coronary artery angiography.Results ABI ≤ 0.9 was seen in 68 patients（8.1%）.The prevalence of atherosclerotic risk factors was significantly higher in ABI≤ 0.9 patients than in ABI 0.9.ABI≤ 0.9 patients had more signif icant stenosis than ABI 0.9 ones.Conclusion The findings of this research indicated that ABI could be a useful method in assessing both the atherosclerotic risk factors and the degree of coronary involvements in suspected patients.

关 键 词：踝臂指数 冠状动脉 粥样硬化 

分 类 号：R541.4[医药卫生—心血管疾病]