百日咳杆菌感染与成人不明原因慢性咳嗽相关性研究现状  

Research progress of Bordetella pertussis infection and chronic cough in adults

作　　者：文芳静[1] 肖锦秀[1] 胡克[1] 

机构地区：[1]武汉大学人民医院呼吸科,武汉430060

出　　处：《国际呼吸杂志》2012年第12期941-945,共5页International Journal of Respiration

摘　　要：尽管咳嗽变异性哮喘、上气道咳嗽综合征／鼻后滴流综合征、嗜酸粒细胞性支气管炎和胃食管反流性咳嗽被普遍认为是不明原因慢性咳嗽（简称慢性咳嗽）最常见病因，但感染后咳嗽也是引起长期咳嗽的一个重要因素。由肺炎支原体和肺炎衣原体等引起的感染后咳嗽多为人们所熟知，且常经验性使用大环内酯类抗生素对其治疗。长期以来，百日咳被认为在儿童呼吸道感染性疾病中较为常见，但近年来的研究表明，百日咳杆菌感染也是引起成人慢性咳嗽的常见原因，需要加以重视和鉴别。Although cough variant asthma, upper airway cough syndrome/postnasal drip syndrome, eosinophilie bronchitis and gastroesophageal reflux disease are generally considered as the most common causes of chronic cough, postinfectious cough is also an important factor. Mycoplasma pneumonia and Chlamydia pneumonia have been well known and we often empirically use maerolides for its treatment. Over the years, pertussis has been commonly considered infectious respiratory disease in children. But recent studies have demonstrated it＇s a common cause of persistent cough in adults and should be considered in differential diagnosis.

关 键 词：百日咳 病因 慢性咳嗽 

分 类 号：R56[医药卫生—呼吸系统]