电热圈环切术(LEEP)诊治宫颈上皮内瘤变的临床价值  

Clinical value of LEEP for diagnosis and treatment of cervical intraepithelial neoplasia

作　　者：陈灼英[1] 谢芳[1] 李珍[1] 林颖[1] 

机构地区：[1]福建省宁德市福安闽东医院福建医科大学临床教学专业基地,355000

出　　处：《中国妇幼保健》2012年第19期3040-3042,共3页Maternal and Child Health Care of China

摘　　要：目的:探讨LEEP诊治宫颈上皮内瘤变(CIN)的临床价值。方法:对门诊收治患者中行TCT、阴道镜、宫颈组织学三阶梯检查确定为宫颈上皮内瘤病变423例进行LEEP治疗及随访分析。结果:423例CIN行LEEP病理结果 CINⅠ、Ⅱ、Ⅲ分别为123例、113例、137例,慢性炎症37例,浸润癌12例(Ⅰa18例、Ⅰa22例、Ⅰb 2例),微偏腺癌1例,术后病理CINⅢ的例数增加,宫颈癌检出率3.07%。同时发现30～39岁年龄段CIN发病率最高,30～39岁与50～59岁年龄段比较发病率差异有统计学意义(P<0.05),余组发病率差异无统计学意义。随访术后1～2个月内CIN的患者宫颈大部分恢复如初,有4例行第2次LEEP,LEEP一次成功率为99.05%,部分患者失访,随访中大部分患者效果满意,未发现CIN复发的病例。结论:LEEP是目前治疗宫颈病变的最佳方法,也是预防及发现早期宫颈癌的有效方法。Objective：To explore the clinical value of loop electrosurgical excision procedure（LEEP） for diagnosis and treatment of cervical intraepithelial neoplasia（CIN）.Methods：A total of 423 cases who were diagnosed as CIN by three-step technique（TCT,colposcope,and cervical cytological test） in outpatient department underwent LEEP,then they were followed up and analyzed.Results：The pathological results of LEEP were CIN Ⅰ（123 patients）,CIN Ⅱ（113 cases）,CIN Ⅲ（137 cases）,chronic inflammation（37 cases）,invasive carcinoma（12 cases,including 8 cases of Ⅰa1,2 cases of Ⅰa2,and 2 cases of Ⅰb）,and minimal deviation adenocarcinoma（one patient）;after operation,the number of cases with CIN Ⅲ found by pathological examination increased,the detection rate of cervical cancer was 3.07%.The incidence of CIN was the highest among the cases aged 30-39 years old,there was significant difference in the incidence of CIN between the cases aged 30-39 years old and the cases aged 50-59 years old（P〈0.05）,there was no significant difference among the other groups.At 1-2-month after operation,the cervix of most cases returned to normal,4 cases underwent secondary LEEP,the one-time success rate of LEEP was 99.05%,partial cases were lost to follow up,the effects of most cases were satisfactory,no recurrence of CIN was found.Conclusion：LEEP is the best method to cure cervical lesions at present,and it is an effective method to prevent and detect early cervical cancer.

关 键 词：电热圈环切术 宫颈上皮内瘤变 治疗 

分 类 号：R711.74[医药卫生—妇产科学]