三妙散加减方配合纤溶酶治疗急性下肢深静脉血栓形成临床研究  

Clinical Research on Sanmiao Powder Combined Fibrinogenase for Injection in Treatment of Acute Deep Venous Thrombosis of Lower Limbs

作　　者：周涛[1] 孙大庆[1] 吴鹏[1] 杨燕菲[1] 孙强[1] 

机构地区：[1]山东大学第二医院周围血管病科,济南250033

出　　处：《中国中西医结合杂志》2012年第7期918-921,共4页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的观察三妙散加减方配合纤溶酶治疗急性下肢深静脉血栓形成(acute deep venous thrombosis,ADVT)的临床效果。方法随机选取ADVT患者80例,以发病时间长短(<7天或7～28天)分为2个时间段,每个时间段40例,每个时间段又分为2组:单纯纤溶酶治疗组(A、C组)和内服三妙散加减方配合纤溶酶治疗组(B、D组),每组20例,治疗2周后观察各组治疗效果。结果内服三妙散加减方配合纤溶酶治疗组在减轻肢体肿胀、缓解疼痛等症状,以及降低纤维蛋白原(Fib)上明显优于单纯纤溶酶治疗组;发病时间<7天临床疗效较>7天更好。结论中西医结合治疗ADVT临床效果较好。Objective To observe the clinical effectiveness of Sanmiao Powder （SP） combined fibrinoge- nase for injection in treatment of acute deep venous thrombosis （ADVT） of lower limbs. Methods Eighty patients with ADVT were randomly assigned to two groups according to the disease course （within7days or 7-28 days）, 40 in each group. Every time phase was also divided into two groups, i. e., one group treated with fibdn- ogenase for injection alone （Group A and C） and another group treated with fibrinogenase for injection ＋ SP ad- ministration （Group B and D）, 20 in each group. The clinical effectiveness was observed after 2-week treatment. Results The fibrinogenase for injection ＋ SP administration showed better effects in alleviating the swelling of limbs, relieving pain, and lowering fibrinogen. Better effects were obtained in the group with the disease course less than 7 days. Conclusion Better effect on ADVT was obtained by integrative medicine.

关 键 词：三妙散 下肢深静脉血栓形成 急性期 中西医结合 治疗 

分 类 号：R543.6[医药卫生—心血管疾病]