丙泊酚联合芬太尼在无痛胃镜检查中不良反应的分析  

The Adverse Effect of the Combination of Propofol and Fentanyl in Painless Gastroscopy

作　　者：王强[1] 李哲华[1] 张雁[1] 

机构地区：[1]广州市番禺区中医院,广东广州511400

出　　处：《辽宁医学院学报》2012年第3期216-217,221,共3页Journal of Liaoning Medical University (LNMU) Bimonthly

摘　　要：目的探讨丙泊酚联合芬太尼在无痛胃镜检查中不良反应的预防和处理。方法 1 000例患者使用丙泊酚联合芬太尼静脉全麻进行胃镜检查,按性别分为两组:男300例,女300例;按年龄分为两组:年龄大于60岁(含60岁)200例,年龄小于60岁200例,观察并处理出现的不良反应。结果不同年龄组、不同性别组血氧饱和度低于90%者发生率比较,年龄≥60岁组明显高于年龄<60岁组的患者,女性组明显高于男性组,差异有统计学意义;不同性别组头晕的发生率比较,女性组明显高于男性组,差异有统计学意义。结论丙泊酚联合芬太尼静脉全麻胃镜检查中应该特别加强对女性、老年人的监护,如发生不良反应及时处理,以减轻不良反应的程度。Objective To explore the prevention and treatment of the adverse effects in painless gastroscopy by com- bining Propofol and Fentanyl. Methods 1 000 patients with Propofol and Fentanyl intravenous anesthesia were examined by Gastroseopy. These patients were divided into two groups according to gender, 300 males and 300 females, the rest pa- tients were divided into two groups according to age, 200 aged 60 or more and 200 under the age of 60. The adverse effects were observed and treated. Results In terms of the incidence of the rate of SPO2, less than 90% patients aged ≥ 60 were significantly higher than those aged 〈 60, female patients were significantly higher than male patients. The difference was statistically significant. In terms of the incidence of dizziness, female patients were significantly higher than male patients. The difference was statistically significant. Conclusion In intravenous anesthesia gastroscopy of Propofol and Fentanyl, it is especially important to enhance the care of female and old patients. Adverse effect should be coped with in a timely man- ner so as to alleviate the degree of adverse effects.

关 键 词：胃镜检查 丙泊酚 芬太尼 不良反应 

分 类 号：R614[医药卫生—麻醉学]