中风安口服液治疗脑血栓急性期的疗效与安全性评价  

Efficacy and safety of oral Zhongfengan liquid in the treatment of acute stage of cerebral thrombosis

作　　者：王兰君[1] 靳隽[2] 

机构地区：[1]新乡医学院第一附属医院,河南卫辉453100 [2]新乡医学院医学检验系,河南新乡453000

出　　处：《中国医院药学杂志》2012年第13期1041-1044,共4页Chinese Journal of Hospital Pharmacy

摘　　要：目的:评价中风安口服液治疗脑血栓急性期的疗效与安全性。方法:用随机双盲单模拟阳性药平行对照的多中心研究,受试者随机分成2组:中风安口服液试验组和五味通栓口服液对照组,疗程4周。结果:治疗4周后,综合疗效:试验组和对照组的总有效率分别为90.82%,83.65%,两组比较差异有显著性(P<0.05)。中医症侯疗效:试验组和对照组总有效率为93.04%,85.58%,两组比较差异有统计学意义(P<0.05)。治疗期间未发生不良事件。结论:中风安口服液治疗脑血栓急性期安全有效。OBJECTIVE To evaluate the efficacy and safety of oral ZhongFengan liquid in the treatment of acute stage of cer- ebral thrombosis. METHODS In a randomized, double blind, double - dummy, muhieenter clinical trial, subjects were en- rolled and randomly divided into two groups. The patients were treated with oral ZhongFengan liquid , or Five flavored throm- bolysis oral liquid for four weeks. RESULTS After treatment, the response rates evaluated by comprehensive effect scale in two groups were 90. 82%, 83.65 % respectively （P〈0. 05）. The response rates evaluated by traditional Chinese medical scale in two groups were 93. 04%,85. 58% respectively （P〈0. 05）. There was no drug-related adverse drug reaction found during the study in two groups. CONCLUSION In the present study the oral ZhongFengan liquid was proved to be safe and effective in the treatment of acute stage of cerebral thrombosis.

关 键 词：中风安口服液 脑血栓急性期 五味通栓口服液 

分 类 号：R285[医药卫生—中药学]