正交试验优选肤宁洗剂提取工艺  

Optimization of the Extraction Technology of Funing Lotion

作　　者：黄慧[1] 顾卫[1] 黄丽雅[1] 翁雪萍[2] 

机构地区：[1]惠州市中医医院,广东惠州516001 [2]惠州市药品检验所,广东惠州516003

出　　处：《中国药房》2012年第27期2522-2523,共2页China Pharmacy

基　　金：惠州市科技计划(医疗卫生)项目(2011Y066)

摘　　要：目的:优选肤宁洗剂的提取工艺。方法:采用水提醇沉法提取,以苦参碱含量为评价指标,以加水量、提取时间、提取次数、醇沉溶液的pH值为考察因素,采用正交试验优选工艺。结果:最佳提取工艺为药材加8倍量水,提取3次,每次提取3h,醇沉溶液pH值为9.5。结论:所选工艺简便、稳定,可用于肤宁洗剂的提取。OBJECTIVE： To optimize the extraction technology of Funing lotion. METHODS： Water extraction and alcohol pre- cipitation was adopted. The extraction technology was optimized by orthogonal design with water added, extraction time, extraction times and pH value of precipitating solution as factors using the content of matrine as index. RESULTS： The best extraction technol- ogy was 8 times water, extracting for 3 times, lasting for 3 h each time, pH value of precipitating solution of 9.5. CONCLU- SION： The optimized process is simple and stable for the extraction of Funing lotion.

关 键 词：肤宁洗剂 正交试验 苦参碱 提取工艺 

分 类 号：R284.2[医药卫生—中药学] R283.6[医药卫生—中医学]