2型糖尿病合并急性脑梗死与血尿酸及血脂水平的临床分析  

Relation of type 2 diabetes mellitus accompanying acute cerebral infarction with serum uric acid and blood lipid level

作　　者：关颖[1] 毕齐[1] 

机构地区：[1]首都医科大学附属北京安贞医院神经内科,100029

出　　处：《中华老年心脑血管病杂志》2012年第7期734-736,共3页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

摘　　要：目的探讨2型糖尿病合并急性脑梗死与血尿酸及血脂水平的关系。方法选择急性脑梗死患者366例,根据有无糖尿病将患者分为2组,2型糖尿病合并急性脑梗死为糖尿病组163例、无糖尿病的急性脑梗死为对照组203例,测定2组患者血尿酸及血脂水平,分析其与2型糖尿病合并急性脑梗死的相关性。结果与对照组比较,糖尿病组血清尿酸水平明显升高,差异有统计学意义[(414.41±45.74)μmol/Lvs(370.54±42.37)μmo1/L,P<0.05];糖尿病组TC、TG、LDL-C水平明显升高,差异有统计学意义(P<0.05,P<0.01)。logistic多元相关分析,糖尿病与血尿酸水平呈负相关(r=-0.484,P=0.017)。结论高尿酸血症和高脂血症是2型糖尿病合并急性脑梗死的危险因素。Objective To study the relation of type 2 diabetes mellitus（DM） accompanying acute cerebral infarction with serum uric acid and blood lipid level. Methods Three hundred and sixty- six acute cerebral infarction patients included in this study were divided into type 2 DM accompan- ying acute cerebral infarction group（DM group,n= 163） and no diabetic acute cerebral infarction group（control group,n=203） according to whether they had DM or not. Their serum levels of uric acid,TG,TC,HDL-C and LDL-C were measured. Relation of thesse parameter with type 2 DM accompanying acute cerebral infarction was analyzed. Results The serum levels of uric acid [（414.41±45.74） μmol/L vs （370.54±42.37） μmol/L], TC, TG and LDL-C were significantly higher in DM group than in control group（P〈0.05,P〈0.01）. Conclusion Hyperuricemia and hyperlipidemia are the risk factors for type 2 DM accompanying acute cerebral infarction.

关 键 词：糖尿病 2型 脑梗死 尿酸 血脂异常 

分 类 号：R587.1[医药卫生—内分泌] R743[医药卫生—内科学]