野芭蕉通络汤对改善高血压患者氧化应激功能紊乱疗效观察  

Observation of Musa acuminate's effect on hypertension patients with oxidatie stress disorders

作　　者：梁烨[1] 李天资[1] 陆高翔[1] 蓝家富[1] 李雪斌[1] 潘兴寿[1] 韦世革[1] 唐雄林[1] 

机构地区：[1]广西省右江民族医学院,百色533000

出　　处：《中华中医药杂志》2012年第7期1967-1969,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金(No.81060028);广西自然科学基金(No.桂科自0542120)~~

摘　　要：目的:探讨野芭蕉治疗高血压左心室肥厚(LVH)患者氧化应激功能紊乱的效果。方法:选取90例LVH患者随机分为治疗1组和治疗2组两组,每组45例,治疗2组给常规西药治疗,治疗1组用西药加野芭蕉中药治疗,于治疗前后检测患者的超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GSH-PX)、丙二醛(MDA)水平,并与42例健康对照组比较。结果:治疗1组治疗前血清SOD、CAT和GSH-PX均值低于对照组MDA均值高于健康对照组(P<0.01),治疗后血清SOD、CAT和GSH-PX水平提高(P<0.01,P<0.05),MDA下降(P<0.05)。结论:野芭蕉通络汤联合西药治疗LVH,对患者的氧化应激功能紊乱有确切的纠正作用。Objective： To explore the effect of Musa acuminata on left ventricular hypertrophy（LVH） patients with oxidatie stress disorders.Methods： 90 cases of LVH patients were randomly divided into treatment group 1 and treatment group 2,Each group of 45 patients,group 2 with western medicine,group 1 with western medicine and Musa acuminata herbal treatment,The superoxide dismutase（SOD）,catalase（CAT）,glutathione peroxidase（GSH-PX） and malondialdehyde（MDA） level of patients were detected before and after treatment,and compared with 42 cases of healthy control group.Results： The mean of serum SOD,CAT and GSH-PX of group 1 before treatment were lower than those of the healthy control group（P〈0.01）;The mean of serum MDA of group 1 before treatment was higher than those of the healthy control group（P〈0.01）.The mean of serum SOD,CAT and GSH-PX of group 2 before treatment were lower than those of the healthy control group（P〈0.01,P〈0.05）,but the mean of serum MDA decrease（P〈0.05）.Conclusion： Musa acuminata integrated with western medicine therapy have the exact corrective action for LVH patients with oxidatie stress disorders.

关 键 词：高血压 氧化应激功能 野芭蕉通络汤 

分 类 号：R285.5[医药卫生—中药学]